Search Results
Overview
| Uniprot ID | Q08851 |
|---|---|
| Protein Name | Syntaxin-5 |
| Gene Name | Stx5 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 10 | PRKRYGSKNTDQGVY |
Function
Mediates endoplasmic reticulum to Golgi transport (PubMed:10930451, PubMed:14742712, PubMed:9506515). Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus (PubMed:18167358)
Protein Sequence
10
MIPRKRYGSK
20
NTDQGVYLGL
30
SKTQVLSPAT
40
AINSSSDIAP
50
LPTPVALVPS
60
PPDTMSCRDR
70
TQEFLSACKS
80
LQSRQNGIQT
90
NKPALHATRQ
100
CSEFTLMARR
110
IGKDLSNTFA
120
KLEKLTILAK
130
RKSLFDDKAV
140
EIEELTYIIK
150
QDINSLNKQI
160
AQLQDFVRAK
170
GSQSGRHLQT
180
HSNTIVVSLQ
190
SKLASMSNDF
200
KSVLEVRTEN
210
LKQQRNRREQ
220
FSRAPVSALP
230
LAPNNLGGGP
240
IVLGGESRAS
250
RDVAIDMMDP
260
RTSQQLQLID
270
EQDSYIQSRA
280
DTMQNIESTI
290
VELGSIFQQL
300
AHMVKEQEET
310
IQRIDENVLG
320
AQLDVEAAHS
330
EILKYFQSVT
340
SNRWLMVKIF
350
LILIVFFIIF
VVFLA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0090166 | Golgi disassembly |
| Biological Process | GO:0006886 | intracellular protein transport |
| Biological Process | GO:0045732 | positive regulation of protein catabolic process |
| Biological Process | GO:1903358 | regulation of Golgi organization |
| Biological Process | GO:0042147 | retrograde transport, endosome to Golgi |
| Biological Process | GO:0006890 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| Biological Process | GO:0048278 | vesicle docking |
| Biological Process | GO:0006906 | vesicle fusion |
| Biological Process | GO:0048280 | vesicle fusion with Golgi apparatus |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0012505 | endomembrane system |
| Cellular Component | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0031201 | SNARE complex |
| Cellular Component | GO:0031982 | vesicle |
| Molecular Function | GO:0005484 | SNAP receptor activity |
| Molecular Function | GO:0000149 | SNARE binding |
| Biological Process | GO:0034498 | early endosome to Golgi transport |
| Biological Process | GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.