Search Results
Overview
| Uniprot ID | Q08877 |
|---|---|
| Protein Name | Dynamin-3 |
| Gene Name | Dnm3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 257 | AAMLAERKFFLSHPA |
| 87 | YAEFLHCKGKKFTDF |
Function
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP (By similarity). Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity)
Protein Sequence
10
MGNREMEELI
20
PLVNRLQDAF
30
SALGQSCLLE
40
LPQIAVVGGQ
50
SAGKSSVLEN
60
FVGRDFLPRG
70
SGIVTRRPLV
80
LQLVTSKAEY
90
AEFLHCKGKK
100
FTDFDEVRHE
110
IEAETDRVTG
120
MNKGISSVPI
130
NLRVYSPHVL
140
NLTLIDLPGI
150
TKVPVGDQPP
160
DIEYQIRDMI
170
MQFITRENCL
180
ILAVTPANTD
190
LANSDALKLA
200
KEVDPQGLRT
210
IGVITKLDLM
220
DEGTDARDVL
230
ENKLLPLRRG
240
YVGVVNRSQK
250
DIDGKKDIKA
260
AMLAERKFFL
270
SHPAYRHIAD
280
RMGTPHLQKV
290
LNQQLTNHIR
300
DTLPNFRNKL
310
QGQLLSIEHE
320
VEAFKNFKPE
330
DPTRKTKALL
340
QMVQQFAVDF
350
EKRIEGSGDQ
360
VDTLELSGGA
370
KINRIFHERF
380
PFEIVKMEFN
390
EKELRREISY
400
AIKNIHGIRT
410
GLFTPDMAFE
420
AIVKKQIVKL
430
KGPSLKSVDL
440
VMQELINTVK
450
KCTKRLANFP
460
RLCEETERIV
470
ANHIREREGK
480
TKDQVLLLID
490
IQVSYINTNH
500
EDFIGFANAQ
510
QRSSQVHKKS
520
TIGNQGTNLP
530
PSRQIVIRKG
540
WLTVSNIGIM
550
KGGSKGYWFV
560
LTAESLSWYK
570
DDEEKEKKYM
580
LPLDNLKVRD
590
VEKGFMSSKH
600
VFALFNTEQR
610
NVYKDYRSLE
620
LACDSQEDVD
630
SWKASLLRAG
640
VYPDKSFTEN
650
DENGQAENFS
660
MDPQLERQVE
670
TIRNLVDSYM
680
SIINKCIRDL
690
IPKTIMHLMI
700
NNVKDFINSE
710
LLAQLYSSED
720
QNTLMEESVE
730
QAQRRDEMLR
740
MYQALKEALA
750
IIGDINTVTV
760
STPAPPPVDD
770
SWLQHSRRSP
780
PPSPTTQRRL
790
TLSAPLPRPA
800
SSRGPAPAIP
810
SPGPHSGAPP
820
VPFRPGPLPP
830
FPNSSDSYGA
840
PPQVPSRPTR
850
APPSVPSRRP
860
PPSPTRPTII
RPLESSLLD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0061828 | apical tubulobulbar complex |
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0061829 | basal tubulobulbar complex |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0031410 | cytoplasmic vesicle |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0043197 | dendritic spine |
| Cellular Component | GO:0044327 | dendritic spine head |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0001917 | photoreceptor inner segment |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0098844 | postsynaptic endocytic zone membrane |
| Cellular Component | GO:0098793 | presynapse |
| Cellular Component | GO:0045202 | synapse |
| Cellular Component | GO:0043083 | synaptic cleft |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0008017 | microtubule binding |
| Molecular Function | GO:0050998 | nitric-oxide synthase binding |
| Molecular Function | GO:0120283 | protein serine/threonine kinase binding |
| Molecular Function | GO:0099186 | structural constituent of postsynapse |
| Molecular Function | GO:0031798 | type 1 metabotropic glutamate receptor binding |
| Molecular Function | GO:0031802 | type 5 metabotropic glutamate receptor binding |
| Biological Process | GO:0006897 | endocytosis |
| Biological Process | GO:0046847 | filopodium assembly |
| Biological Process | GO:0061002 | negative regulation of dendritic spine morphogenesis |
| Biological Process | GO:0051491 | positive regulation of filopodium assembly |
| Biological Process | GO:1903423 | positive regulation of synaptic vesicle recycling |
| Biological Process | GO:0061001 | regulation of dendritic spine morphogenesis |
| Biological Process | GO:0042713 | sperm ejaculation |
| Biological Process | GO:0007416 | synapse assembly |
| Biological Process | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane |
| Biological Process | GO:0048488 | synaptic vesicle endocytosis |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.