Search Results

Overview

Uniprot IDQ10464
Protein NamePuroindoline-B
Gene NamePINB
OrganismTriticum aestivum

Kla Sites from experimental identification

Position Flanking peptide
133 RAQSLPSKCNMGADC
46 QCPQERPKLSSCKDY

Function

Acts as a membranotoxin, probably through its antibacterial and antifungal activities, contributing to the defense mechanism of the plant against predators. Forms monovalent cation-selective ion channels in membranes. Has antibacterial activity against the Gram-positive bacteria S.aureus and C.michiganensis, and the Gram-negative bacteria E.coli, P.syringae pv phaseoli, A.tumefaciens and E.carotovora subsp carotovora. Acts synergistically with PINA against bacteria. Contributes to grain texture and hardness

Protein Sequence

10 MKTLFLLALL 20 ALVASTTFAQ 30 YSEVGGWYNE 40 VGGGGGSQQC 50 PQERPKLSSC 60 KDYVMERCFT 70 MKDFPVTWPT 80 KWWKGGCEHE 90 VREKCCKQLS 100 QIAPQCRCDS 110 IRRVIQGRLG 120 GFLGIWRGEV 130 FKQLQRAQSL 140 PSKCNMGADC KFPSGYYW

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0016020 membrane
Molecular Function GO:0045735 nutrient reservoir activity
Molecular Function GO:0004867 serine-type endopeptidase inhibitor activity
Molecular Function GO:0090729 toxin activity
Biological Process GO:0042742 defense response to bacterium

Reference

[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.