Search Results
Overview
| Uniprot ID | Q12864 |
|---|---|
| Protein Name | Cadherin-17 |
| Gene Name | CDH17 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 32 | GKFSGPLKPMTFSIY |
| 331 | LEIHVKVKDINDNPP |
Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport
Protein Sequence
10
MILQAHLHSL
20
CLLMLYLATG
30
YGQEGKFSGP
40
LKPMTFSIYE
50
GQEPSQIIFQ
60
FKANPPAVTF
70
ELTGETDNIF
80
VIEREGLLYY
90
NRALDRETRS
100
THNLQVAALD
110
ANGIIVEGPV
120
PITIKVKDIN
130
DNRPTFLQSK
140
YEGSVRQNSR
150
PGKPFLYVNA
160
TDLDDPATPN
170
GQLYYQIVIQ
180
LPMINNVMYF
190
QINNKTGAIS
200
LTREGSQELN
210
PAKNPSYNLV
220
ISVKDMGGQS
230
ENSFSDTTSV
240
DIIVTENIWK
250
APKPVEMVEN
260
STDPHPIKIT
270
QVRWNDPGAQ
280
YSLVDKEKLP
290
RFPFSIDQEG
300
DIYVTQPLDR
310
EEKDAYVFYA
320
VAKDEYGKPL
330
SYPLEIHVKV
340
KDINDNPPTC
350
PSPVTVFEVQ
360
ENERLGNSIG
370
TLTAHDRDEE
380
NTANSFLNYR
390
IVEQTPKLPM
400
DGLFLIQTYA
410
GMLQLAKQSL
420
KKQDTPQYNL
430
TIEVSDKDFK
440
TLCFVQINVI
450
DINDQIPIFE
460
KSDYGNLTLA
470
EDTNIGSTIL
480
TIQATDADEP
490
FTGSSKILYH
500
IIKGDSEGRL
510
GVDTDPHTNT
520
GYVIIKKPLD
530
FETAAVSNIV
540
FKAENPEPLV
550
FGVKYNASSF
560
AKFTLIVTDV
570
NEAPQFSQHV
580
FQAKVSEDVA
590
IGTKVGNVTA
600
KDPEGLDISY
610
SLRGDTRGWL
620
KIDHVTGEIF
630
SVAPLDREAG
640
SPYRVQVVAT
650
EVGGSSLSSV
660
SEFHLILMDV
670
NDNPPRLAKD
680
YTGLFFCHPL
690
SAPGSLIFEA
700
TDDDQHLFRG
710
PHFTFSLGSG
720
SLQNDWEVSK
730
INGTHARLST
740
RHTEFEEREY
750
VVLIRINDGG
760
RPPLEGIVSL
770
PVTFCSCVEG
780
SCFRPAGHQT
790
GIPTVGMAVG
800
ILLTTLLVIG
810
IILAVVFIRI
820
KKDKGKDNVE
830
SAQASEVKPL
RS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005912 | adherens junction |
| Cellular Component | GO:0016323 | basolateral plasma membrane |
| Cellular Component | GO:0016342 | catenin complex |
| Cellular Component | GO:0030054 | cell junction |
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0008013 | beta-catenin binding |
| Molecular Function | GO:0045296 | cadherin binding |
| Molecular Function | GO:0005509 | calcium ion binding |
| Molecular Function | GO:0005178 | integrin binding |
| Molecular Function | GO:0005427 | proton-dependent oligopeptide secondary active transmembrane transporter activity |
| Biological Process | GO:0034332 | adherens junction organization |
| Biological Process | GO:0016339 | calcium-dependent cell-cell adhesion |
| Biological Process | GO:0007155 | cell adhesion |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0000902 | cell morphogenesis |
| Biological Process | GO:0044331 | cell-cell adhesion mediated by cadherin |
| Biological Process | GO:0007043 | cell-cell junction assembly |
| Biological Process | GO:0002314 | germinal center B cell differentiation |
| Biological Process | GO:0007156 | homophilic cell-cell adhesion |
| Biological Process | GO:0007229 | integrin-mediated signaling pathway |
| Biological Process | GO:0002315 | marginal zone B cell differentiation |
| Biological Process | GO:0033626 | positive regulation of integrin activation by cell surface receptor linked signal transduction |
| Biological Process | GO:0048536 | spleen development |
Reference
PMID: N/A