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Overview

Uniprot IDQ13242
Protein NameSerine/arginine-rich splicing factor 9
Gene NameSRSF9
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
144 VCYADVQKDGVGMVE

Function

Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10

Protein Sequence

10 MSGWADERGG 20 EGDGRIYVGN 30 LPTDVREKDL 40 EDLFYKYGRI 50 REIELKNRHG 60 LVPFAFVRFE 70 DPRDAEDAIY 80 GRNGYDYGQC 90 RLRVEFPRTY 100 GGRGGWPRGG 110 RNGPPTRRSD 120 FRVLVSGLPP 130 SGSWQDLKDH 140 MREAGDVCYA 150 DVQKDGVGMV 160 EYLRKEDMEY 170 ALRKLDDTKF 180 RSHEGETSYI 190 RVYPERSTSY 200 GYSRSRSGSR 210 GRDSPYQSRG 220 SPHYFSPFRP Y

Gene Ontology

Classification GO ID Description
Cellular Component GO:0016607 nuclear speck
Cellular Component GO:0005654 nucleoplasm
Molecular Function GO:0003729 mRNA binding
Molecular Function GO:0019904 protein domain specific binding
Molecular Function GO:0003723 RNA binding
Biological Process GO:0006397 mRNA processing
Biological Process GO:0006376 mRNA splice site recognition
Biological Process GO:0048025 negative regulation of mRNA splicing, via spliceosome
Biological Process GO:0000381 regulation of alternative mRNA splicing, via spliceosome

Reference

PMID: N/A