Search Results
Overview
| Uniprot ID | Q13939 |
|---|---|
| Protein Name | Calicin |
| Gene Name | CCIN |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 400 | IYRYDERKEVWCLAG |
Function
Required for both nuclear and acrosomal shaping during spermiogenesis
Protein Sequence
10
MKLEFTEKNY
20
NSFVLQNLNR
30
QRKRKEYWDM
40
ALSVDNHVFF
50
AHRNVLAAVS
60
PLVRSLISSN
70
DMKTADELFI
80
TIDTSYLSPV
90
TVDQLLDYFY
100
SGKVVISEQN
110
VEELLRGAQY
120
FNTPRLRVHC
130
NDFLIKSICR
140
ANCLRYLFLA
150
ELFELKEVSD
160
VAYSGIRDNF
170
HYWASPEGSM
180
HFMRCPPVIF
190
GRLLRDENLH
200
VLNEDQALSA
210
LINWVYFRKE
220
DREKYFKKFF
230
NYINLNAVSN
240
KTLVFASNKL
250
VGMENTSSHT
260
TLIESVLMDR
270
KQERPCSLLV
280
YQRKGALLDS
290
VVILGGQKAH
300
GQFNDGVFAY
310
IIQENLWMKL
320
SDMPYRAAAL
330
SATSAGRYIY
340
ISGGTTEQIS
350
GLKTAWRYDM
360
DDNSWTKLPD
370
LPIGLVFHTM
380
VTCGGTVYSV
390
GGSIAPRRYV
400
SNIYRYDERK
410
EVWCLAGKMS
420
IPMDGTAVIT
430
KGDRHLYIVT
440
GRCLVKGYIS
450
RVGVVDCFDT
460
STGDVVQCIT
470
FPIEFNHRPL
480
LSFQQDNILC
490
VHSHRQSVEI
500
NLQKVKASKT
510
TTSVPVLPNS
520
CPLDVSHAIC
530
SIGDSKVFVC
540
GGVTTASDVQ
550
TKDYTINPNA
560
FLLDQKTGKW
570
KTLAPPPEAL
580
DCPACCLAKL
PCKILQRI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031463 | Cul3-RING ubiquitin ligase complex |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0033150 | cytoskeletal calyx |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0033011 | perinuclear theca |
| Cellular Component | GO:0120238 | sperm glycocalyx |
| Molecular Function | GO:1990756 | ubiquitin-like ligase-substrate adaptor activity |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0007283 | spermatogenesis |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.