Search Results

Overview

Uniprot IDQ14119
Protein NameVascular endothelial zinc finger 1
Gene NameVEZF1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
375 RLWEEAVKARKKEAA

Function

Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3

Protein Sequence

10 MEANWTAFLF 20 QAHEASHHQQ 30 QAAQNSLLPL 40 LSSAVEPPDQ 50 KPLLPIPITQ 60 KPQGAPETLK 70 DAIGIKKEKP 80 KTSFVCTYCS 90 KAFRDSYHLR 100 RHESCHTGIK 110 LVSRPKKTPT 120 TVVPLISTIA 130 GDSSRTSLVS 140 TIAGILSTVT 150 TSSSGTNPSS 160 SASTTAMPVT 170 QSVKKPSKPV 180 KKNHACEMCG 190 KAFRDVYHLN 200 RHKLSHSDEK 210 PFECPICNQR 220 FKRKDRMTYH 230 VRSHEGGITK 240 PYTCSVCGKG 250 FSRPDHLSCH 260 VKHVHSTERP 270 FKCQTCTAAF 280 ATKDRLRTHM 290 VRHEGKVSCN 300 ICGKLLSAAY 310 ITSHLKTHGQ 320 SQSINCNTCK 330 QGISKTCMSE 340 ETSNQKQQQQ 350 QQQQQQQQQQ 360 QQQQHVTSWP 370 GKQVETLRLW 380 EEAVKARKKE 390 AANLCQTSTA 400 ATTPVTLTTP 410 FSITSSVSSG 420 TMSNPVTVAA 430 AMSMRSPVNV 440 SSAVNITSPM 450 NIGHPVTITS 460 PLSMTSPLTL 470 TTPVNLPTPV 480 TAPVNIAHPV 490 TITSPMNLPT 500 PMTLAAPLNI 510 AMRPVESMPF 520 LPQALPTSPP W

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
Molecular Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006968 cellular defense response
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0045603 positive regulation of endothelial cell differentiation
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0006357 regulation of transcription by RNA polymerase II

Reference

PMID: N/A