Search Results
Overview
| Uniprot ID | Q14135 |
|---|---|
| Protein Name | Transcription cofactor vestigial-like protein 4 |
| Gene Name | VGLL4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 76 | CDNDHVSKMSRIFNP |
| 87 | IFNPHLNKTANGDCR |
Function
May act as a specific coactivator for the mammalian TEFs
Protein Sequence
10
METPLDVLSR
20
AASLVHADDE
30
KREAALRGEP
40
RIQTLPVASA
50
LSSHRTGPPP
60
ISPSKRKFSM
70
EPGDEDLDCD
80
NDHVSKMSRI
90
FNPHLNKTAN
100
GDCRRDPRER
110
SRSPIERAVA
120
PTMSLHGSHL
130
YTSLPSLGLE
140
QPLALTKNSL
150
DASRPAGLSP
160
TLTPGERQQN
170
RPSVITCASA
180
GARNCNLSHC
190
PIAHSGCAAP
200
GPASYRRPPS
210
AATTCDPVVE
220
EHFRRSLGKN
230
YKEPEPAPNS
240
VSITGSVDDH
250
FAKALGDTWL
260
QIKAAKDGAS
270
SSPESASRRG
280
QPASPSAHMV
290
SHSHSPSVVS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0001223 | transcription coactivator binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0060044 | negative regulation of cardiac muscle cell proliferation |
| Biological Process | GO:0030308 | negative regulation of cell growth |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
| Biological Process | GO:0035331 | negative regulation of hippo signaling |
| Biological Process | GO:0030178 | negative regulation of Wnt signaling pathway |
| Biological Process | GO:0045732 | positive regulation of protein catabolic process |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.