Search Results
Overview
| Uniprot ID | Q14161 |
|---|---|
| Protein Name | ARF GTPase-activating protein GIT2 |
| Gene Name | GIT2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 464 | ELRIMQKKLQTLQSE |
Function
GTPase-activating protein for ADP ribosylation factor family members, including ARF1
Protein Sequence
10
MSKRLRSSEV
20
CADCSGPDPS
30
WASVNRGTFL
40
CDECCSVHRS
50
LGRHISQVRH
60
LKHTPWPPTL
70
LQMVETLYNN
80
GANSIWEHSL
90
LDPASIMSGR
100
RKANPQDKVH
110
PNKAEFIRAK
120
YQMLAFVHRL
130
PCRDDDSVTA
140
KDLSKQLHSS
150
VRTGNLETCL
160
RLLSLGAQAN
170
FFHPEKGNTP
180
LHVASKAGQI
190
LQAELLAVYG
200
ADPGTQDSSG
210
KTPVDYARQG
220
GHHELAERLV
230
EIQYELTDRL
240
AFYLCGRKPD
250
HKNGQHFIIP
260
QMADSSLDLS
270
ELAKAAKKKL
280
QSLSNHLFEE
290
LAMDVYDEVD
300
RRETDAVWLA
310
TQNHSALVTE
320
TTVVPFLPVN
330
PEYSSTRNQG
340
RQKLARFNAH
350
EFATLVIDIL
360
SDAKRRQQGS
370
SLSGSKDNVE
380
LILKTINNQH
390
SVESQDNDQP
400
DYDSVASDED
410
TDLETTASKT
420
NRQKSLDSDL
430
SDGPVTVQEF
440
MEVKNALVAS
450
EAKIQQLMKV
460
NNNLSDELRI
470
MQKKLQTLQS
480
ENSNLRKQAT
490
TNVYQVQTGS
500
EYTDTSNHSS
510
LKRRPSARGS
520
RPMSMYETGS
530
GQKPYLPMGE
540
ASRPEESRMR
550
LQPFPAHIGR
560
SALVTSSSSL
570
PSFPSTLSWS
580
RDESARRASR
590
LEKQNSTPES
600
DYDNTPNDME
610
PDGMGSSRKG
620
RQRSMVWPGD
630
GLVPDTAEPH
640
VAPSPTLPST
650
EDVIRKTEQI
660
TKNIQELLRA
670
AQENKHDSYI
680
PCSERIHVAV
690
TEMAALFPKK
700
PKSDMVRTSL
710
RLLTSSAYRL
720
QSECKKTLPG
730
DPGSPTDVQL
740
VTQQVIQCAY
750
DIAKAAKQLV
TITTKENNN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0098793 | presynapse |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0031267 | small GTPase binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0007420 | brain development |
| Biological Process | GO:0032012 | regulation of ARF protein signal transduction |
| Biological Process | GO:0008277 | regulation of G protein-coupled receptor signaling pathway |
| Biological Process | GO:0036465 | synaptic vesicle recycling |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.