Search Results

Overview

Uniprot IDQ14202
Protein NameZinc finger MYM-type protein 3
Gene NameZMYM3
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
1086 YANGETSKGDELRFG
308 GRSAVGTKMTCAHCR
320 HCRTPLQKGQTAYQR
439 CSDSCFSKFRANKGL
447 FRANKGLKTNCCDQC
804 EENGNLGKIPVKTRS
808 NLGKIPVKTRSAPTA

Function

Required for regulation of cell morphology and cytoskeletal organization

Protein Sequence

10 MDPSDFPSPF 20 DPLTLPEKPL 30 AGDLPVDMEF 40 GEDLLESQTA 50 PTRGWAPPGP 60 SPSSGALDLL 70 DTPAGLEKDP 80 GVLDGATELL 90 GLGGLLYKAP 100 SPPEVDHGPE 110 GTLAWDAGDQ 120 TLEPGPGGQT 130 PEVVPPDPGA 140 GANSCSPEGL 150 LEPLAPDSPI 160 TLQSPHIEEE 170 ETTSIATARR 180 GSPGQEEELP 190 QGQPQSPNAP 200 PSPSVGETLG 210 DGINSSQTKP 220 GGSSPPAHPS 230 LPGDGLTAKA 240 SEKPPERKRS 250 ERVRRAEPPK 260 PEVVDSTESI 270 PVSDEDSDAM 280 VDDPNDEDFV 290 PFRPRRSPRM 300 SLRSSVSQRA 310 GRSAVGTKMT 320 CAHCRTPLQK 330 GQTAYQRKGL 340 PQLFCSSSCL 350 TTFSKKPSGK 360 KTCTFCKKEI 370 WNTKDSVVAQ 380 TGSGGSFHEF 390 CTSVCLSLYE 400 AQQQRPIPQS 410 GDPADATRCS 420 ICQKTGEVLH 430 EVSNGSVVHR 440 LCSDSCFSKF 450 RANKGLKTNC 460 CDQCGAYIYT 470 KTGSPGPELL 480 FHEGQQKRFC 490 NTTCLGAYKK 500 KNTRVYPCVW 510 CKTLCKNFEM 520 LSHVDRNGKT 530 SLFCSLCCTT 540 SYKVKQAGLT 550 GPPRPCSFCR 560 RSLSDPCYYN 570 KVDRTVYQFC 580 SPSCWTKFQR 590 TSPEGGIHLS 600 CHYCHSLFSG 610 KPEVLDWQDQ 620 VFQFCCRDCC 630 EDFKRLRGVV 640 SQCEHCRQEK 650 LLHEKLRFSG 660 VEKSFCSEGC 670 VLLYKQDFTK 680 KLGLCCITCT 690 YCSQTCQRGV 700 TEQLDGSTWD 710 FCSEDCKSKY 720 LLWYCKAARC 730 HACKRQGKLL 740 ETIHWRGQIR 750 HFCNQQCLLR 760 FYSQQNQPNL 770 DTQSGPESLL 780 NSQSPESKPQ 790 TPSQTKVENS 800 NTVRTPEENG 810 NLGKIPVKTR 820 SAPTAPTPPP 830 PPPPATPRKN 840 KAAMCKPLMQ 850 NRGVSCKVEM 860 KSKGSQTEEW 870 KPQVIVLPIP 880 VPIFVPVPMH 890 LYCQKVPVPF 900 SMPIPVPVPM 910 FLPTTLESTD 920 KIVETIEELK 930 VKIPSNPLEA 940 DILAMAEMIA 950 EAEELDKASS 960 DLCDLVSNQS 970 AEGLLEDCDL 980 FGPARDDVLA 990 MAVKMANVLD 1000 EPGQDLEADF 1010 PKNPLDINPS 1020 VDFLFDCGLV 1030 GPEDVSTEQD 1040 LPRTMRKGQK 1050 RLVLSESCSR 1060 DSMSSQPSCT 1070 GLNYSYGVNA 1080 WKCWVQSKYA 1090 NGETSKGDEL 1100 RFGPKPMRIK 1110 EDILACSAAE 1120 LNYGLAQFVR 1130 EITRPNGERY 1140 EPDSIYYLCL 1150 GIQQYLLENN 1160 RMVNIFTDLY 1170 YLTFVQELNK 1180 SLSTWQPTLL 1190 PNNTVFSRVE 1200 EEHLWECKQL 1210 GVYSPFVLLN 1220 TLMFFNTKFF 1230 GLQTAEEHMQ 1240 LSFTNVVRQS 1250 RKCTTPRGTT 1260 KVVSIRYYAP 1270 VRQRKGRDTG 1280 PGKRKREDEA 1290 PILEQRENRM 1300 NPLRCPVKFY 1310 EFYLSKCPES 1320 LRTRNDVFYL 1330 QPERSCIAES 1340 PLWYSVIPMD 1350 RSMLESMLNR 1360 ILAVREIYEE 1370 LGRPGEEDLD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0008270 zinc ion binding

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[3] Bao Q, Wan N, He Z, Cao J, Yuan W et al.. Subcellular Proteomic Mapping of Lysine Lactylation.. J Am Soc Mass Spectrom 35(12):3221-3232. 2024 Dec 4. PMID: 39569522.

[4] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.