Search Results
Overview
| Uniprot ID | Q14244 |
|---|---|
| Protein Name | Ensconsin |
| Gene Name | MAP7 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 189 | VSTMNLSKYVDPVIS |
Function
Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments
Protein Sequence
10
MAELGAGGDG
20
HRGGDGAVRS
30
ETAPDSYKVQ
40
DKKNASSRPA
50
SAISGQNNNH
60
SGNKPDPPPV
70
LRVDDRQRLA
80
RERREEREKQ
90
LAAREIVWLE
100
REERARQHYE
110
KHLEERKKRL
120
EEQRQKEERR
130
RAAVEEKRRQ
140
RLEEDKERHE
150
AVVRRTMERS
160
QKPKQKHNRW
170
SWGGSLHGSP
180
SIHSADPDRR
190
SVSTMNLSKY
200
VDPVISKRLS
210
SSSATLLNSP
220
DRARRLQLSP
230
WESSVVNRLL
240
TPTHSFLARS
250
KSTAALSGEA
260
ASCSPIIMPY
270
KAAHSRNSMD
280
RPKLFVTPPE
290
GSSRRRIIHG
300
TASYKKERER
310
ENVLFLTSGT
320
RRAVSPSNPK
330
ARQPARSRLW
340
LPSKSLPHLP
350
GTPRPTSSLP
360
PGSVKAAPAQ
370
VRPPSPGNIR
380
PVKREVKVEP
390
EKKDPEKEPQ
400
KVANEPSLKG
410
RAPLVKVEEA
420
TVEERTPAEP
430
EVGPAAPAMA
440
PAPASAPAPA
450
SAPAPAPVPT
460
PAMVSAPSST
470
VNASASVKTS
480
AGTTDPEEAT
490
RLLAEKRRLA
500
REQREKEERE
510
RREQEELERQ
520
KREELAQRVA
530
EERTTRREEE
540
SRRLEAEQAR
550
EKEEQLQRQA
560
EERALREREE
570
AERAQRQKEE
580
EARVREEAER
590
VRQEREKHFQ
600
REEQERLERK
610
KRLEEIMKRT
620
RRTEATDKKT
630
SDQRNGDIAK
640
GALTGGTEVS
650
ALPCTTNAPG
660
NGKPVGSPHV
670
VTSHQSKVTV
680
ESTPDLEKQP
690
NENGVSVQNE
700
NFEEIINLPI
710
GSKPSRLDVT
720
NSESPEIPLN
730
PILAFDDEGT
740
LGPLPQVDGV
QTQQTAEVI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0016323 | basolateral plasma membrane |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0005875 | microtubule associated complex |
| Cellular Component | GO:0015630 | microtubule cytoskeleton |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0005102 | signaling receptor binding |
| Molecular Function | GO:0005198 | structural molecule activity |
| Biological Process | GO:0007163 | establishment or maintenance of cell polarity |
| Biological Process | GO:0000226 | microtubule cytoskeleton organization |
| Biological Process | GO:0072659 | protein localization to plasma membrane |
| Biological Process | GO:0006970 | response to osmotic stress |
Reference
[1] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.