Search Results
Overview
| Uniprot ID | Q14558 |
|---|---|
| Protein Name | Phosphoribosyl pyrophosphate synthase-associated protein 1 |
| Gene Name | PRPSAP1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 36 | RLGAELGKSVVYQET |
Function
Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis
Protein Sequence
10
MNAARTGYRV
20
FSANSTAACT
30
ELAKRITERL
40
GAELGKSVVY
50
QETNGETRVE
60
IKESVRGQDI
70
FIIQTIPRDV
80
NTAVMELLIM
90
AYALKTACAR
100
NIIGVIPYFP
110
YSKQSKMRKR
120
GSIVCKLLAS
130
MLAKAGLTHI
140
ITMDLHQKEI
150
QGFFSFPVDN
160
LRASPFLLQY
170
IQEEIPNYRN
180
AVIVAKSPDA
190
AKRAQSYAER
200
LRLGLAVIHG
210
EAQCTELDMD
220
DGRHSPPMVK
230
NATVHPGLEL
240
PLMMAKEKPP
250
ITVVGDVGGR
260
IAIIVDDIID
270
DVESFVAAAE
280
ILKERGAYKI
290
YVMATHGILS
300
AEAPRLIEES
310
SVDEVVVTNT
320
VPHEVQKLQC
330
PKIKTVDISL
340
ILSEAIRRIH
350
NGESMAYLFR
NITVDD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0004857 | enzyme inhibitor activity |
| Molecular Function | GO:0030234 | enzyme regulator activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Biological Process | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process |
| Biological Process | GO:0006139 | nucleobase-containing compound metabolic process |
| Biological Process | GO:0006164 | purine nucleotide biosynthetic process |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.