Search Results

Overview

Uniprot IDQ14687
Protein NameGenetic suppressor element 1
Gene NameGSE1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
101 SSPASTPKRVPMGPI
1013 HSTNGKSKPWEPFVA
1043 QKALQKHKGSVAVLS
1213 HWPRGYLKGYPR***
441 PTRAEKLKDAGLQAP
624 QAAVPLVKVERVFCP
633 ERVFCPEKAEEGPRK
69 AALRKLAKQAEEPRG
739 QRRRLVSKLDLEERR
896 MLRAMKQKALSAAVA
951 PKAAEPGKLEQVRPQ
973 LAPASGEKARLSEAP
983 LSEAPGGKKSLSMLH
998 YIRGAAPKDIPVPLS

Function

No function data available.

Protein Sequence

10 MKGMSHEPKS 20 PSLGMLSTAT 30 RTTATVNPLT 40 PSPLNGALVP 50 SGSPATSSAL 60 SAQAAPSSSF 70 AAALRKLAKQ 80 AEEPRGSSLS 90 SESSPVSSPA 100 TNHSSPASTP 110 KRVPMGPIIV 120 PPGGHSVPST 130 PPVVTIAPTK 140 TVNGVWRSES 150 RQDAGSRSSS 160 GGRERLIVEP 170 PLPQEKAGGP 180 AIPSHLLSTP 190 YPFGLSPSSV 200 VQDSRFPPLN 210 LQRPVHHVVP 220 PSTVTEDYLR 230 SFRPYHTTDD 240 LRMSSLPPLG 250 LDPATAAAYY 260 HPSYLAPHPF 270 PHPAFRMDDS 280 YCLSALRSPF 290 YPIPTPGSLP 300 PLHPSAMHLH 310 LSGVRYPPEL 320 SHSSLAALHS 330 ERMSGLSAER 340 LQMDEELRRE 350 RERERERERE 360 READREREKE 370 REREREKERE 380 QEKEREREKE 390 RERELERQRE 400 QRAREKELLA 410 AKALEPSFLP 420 VAELHGLRGH 430 ATEERGKPSE 440 QLTPTRAEKL 450 KDAGLQAPKP 460 VQHPLHPVPT 470 PHHTVPSLIS 480 NHGIFSLPSS 490 SAATALLIQR 500 TNEEEKWLAR 510 QRRLRQEKED 520 RQSQVSEFRQ 530 QVLEQHLDMG 540 RPPVPAEAEH 550 RPESTTRPGP 560 NRHEPGGRDP 570 PQHFGGPPPL 580 ISPKPQLHAA 590 PTALWNPVSL 600 MDNTLETRRA 610 ESHSLHSHPA 620 AFEPSRQAAV 630 PLVKVERVFC 640 PEKAEEGPRK 650 REPAPLDKYQ 660 PPPPPPREGG 670 SLEHQPFLPG 680 PGPFLAELEK 690 STQTILGQQR 700 ASLPQAATFG 710 ELSGPLKPGS 720 PYRPPVPRAP 730 DPAYIYDEFL 740 QQRRRLVSKL 750 DLEERRRREA 760 QEKGYYYDLD 770 DSYDESDEEE 780 VRAHLRCVAE 790 QPPLKLDTSS 800 EKLEFLQLFG 810 LTTQQQKEEL 820 VAQKRRKRRR 830 MLRERSPSPP 840 TIQSKRQTPS 850 PRLALSTRYS 860 PDEMNNSPNF 870 EEKKKFLTIF 880 NLTHISAEKR 890 KDKERLVEML 900 RAMKQKALSA 910 AVADSLTNSP 920 RDSPAVSLSE 930 PATQQASLDV 940 EKPVGVAASL 950 SDIPKAAEPG 960 KLEQVRPQEL 970 SRVQELAPAS 980 GEKARLSEAP 990 GGKKSLSMLH 1000 YIRGAAPKDI 1010 PVPLSHSTNG 1020 KSKPWEPFVA 1030 EEFAHQFHES 1040 VLQSTQKALQ 1050 KHKGSVAVLS 1060 AEQNHKVDTS 1070 VHYNIPELQS 1080 SSRAPPPQHN 1090 GQQEPPTARK 1100 GPPTQELDRD 1110 SEEEEEEDDE 1120 DGEDEEEVPK 1130 RKWQGIEAVF 1140 EAYQEHIEEQ 1150 NLERQVLQTQ 1160 CRRLEARHYS 1170 LSLTAEQLSH 1180 SVAELRSQKQ 1190 KMVSERERLQ 1200 AELDHLRKCL 1210 ALPAMHWPRG YLKGYPR

Gene Ontology

No Gene Ontology data available.

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[3] Yang YH, Wang QC, Kong J, Yang JT, Liu JF. Global profiling of lysine lactylation in human lungs.. Proteomics 23(15):e2200437. 2023 Aug. PMID: 37170646.

[4] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[5] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.

[6] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.