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Overview

Uniprot IDQ15390
Protein NameMitochondrial fission regulator 1
Gene NameMTFR1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
227 NAGKTLVKNNPKKPE

Function

May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission (By similarity)

Protein Sequence

10 MLGWIKRLIR 20 MVFQQVGVSM 30 QSVLWSRKPY 40 GSSRSIVRKI 50 GTNLSLIQCP 60 RVQFQINSHA 70 TEWSPSHPGE 80 DAVASFADVG 90 WVAKEEGECS 100 ARLRTEVRSR 110 PPLQDDLLFF 120 EKAPSRQISL 130 PDLSQEEPQL 140 KTPALANEEA 150 LQKICALENE 160 LAALRAQIAK 170 IVTQQEQQNL 180 TAGDLDSTTF 190 GTIPPHPPPP 200 PPPLPPPALG 210 LHQSTSAVDL 220 IKERREKRAN 230 AGKTLVKNNP 240 KKPEMPNMLE 250 ILKEMNSVKL 260 RSVKRSEQDV 270 KPKPVDATDP 280 AALIAEALKK 290 KFAYRYRSDS 300 QDEVEKGIPK 310 SESEATSERV 320 LFGPHMLKPT 330 GKMKALIENV SDS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0005886 plasma membrane
Biological Process GO:0009060 aerobic respiration
Biological Process GO:0000266 mitochondrial fission
Biological Process GO:0007005 mitochondrion organization

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.