Search Results
Overview
| Uniprot ID | Q15398 |
|---|---|
| Protein Name | Disks large-associated protein 5 |
| Gene Name | DLGAP5 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 214 | RSATQAAKQVPRTVS |
| 83 | NVKPRAMKTILGDQR |
Function
Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells
Protein Sequence
10
MSSSHFASRH
20
RKDISTEMIR
30
TKIAHRKSLS
40
QKENRHKEYE
50
RNRHFGLKDV
60
NIPTLEGRIL
70
VELDETSQGL
80
VPEKTNVKPR
90
AMKTILGDQR
100
KQMLQKYKEE
110
KQLQKLKEQR
120
EKAKRGIFKV
130
GRYRPDMPCF
140
LLSNQNAVKA
150
EPKKAIPSSV
160
RITRSKAKDQ
170
MEQTKIDNES
180
DVRAIRPGPR
190
QTSEKKVSDK
200
EKKVVQPVMP
210
TSLRMTRSAT
220
QAAKQVPRTV
230
SSTTARKPVT
240
RAANENEPEG
250
KVPSKGRPAK
260
NVETKPDKGI
270
SCKVDSEENT
280
LNSQTNATSG
290
MNPDGVLSKM
300
ENLPEINTAK
310
IKGKNSFAPK
320
DFMFQPLDGL
330
KTYQVTPMTP
340
RSANAFLTPS
350
YTWTPLKTEV
360
DESQATKEIL
370
AQKCKTYSTK
380
TIQQDSNKLP
390
CPLGPLTVWH
400
EEHVLNKNEA
410
TTKNLNGLPI
420
KEVPSLERNE
430
GRIAQPHHGV
440
PYFRNILQSE
450
TEKLTSHCFE
460
WDRKLELDIP
470
DDAKDLIRTA
480
VGQTRLLMKE
490
RFKQFEGLVD
500
DCEYKRGIKE
510
TTCTDLDGFW
520
DMVSFQIEDV
530
IHKFNNLIKL
540
EESGWQVNNN
550
MNHNMNKNVF
560
RKKVVSGIAS
570
KPKQDDAGRI
580
AARNRLAAIK
590
NAMRERIRQE
600
ECAETAVSVI
610
PKEVDKIVFD
620
AGFFRVESPV
630
KLFSGLSVSS
640
EGPSQRLGTP
650
KSVNKAVSQS
660
RNEMGIPQQT
670
TSPENAGPQN
680
TKSEHVKKTL
690
FLSIPESRSS
700
IEDAQCPGLP
710
DLIEENHVVN
720
KTDLKVDCLS
730
SERMSLPLLA
740
GGVADDINTN
750
KKEGISDVVE
760
GMELNSSITS
770
QDVLMSSPEK
780
NTASQNSILE
790
EGETKISQSE
800
LFDNKSLTTE
810
CHLLDSPGLN
820
CSNPFTQLER
830
RHQEHARHIS
840
FGGNLITFSP
LQPGEF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0072686 | mitotic spindle |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0031616 | spindle pole centrosome |
| Molecular Function | GO:0008017 | microtubule binding |
| Biological Process | GO:0051642 | centrosome localization |
| Biological Process | GO:0007059 | chromosome segregation |
| Biological Process | GO:0051382 | kinetochore assembly |
| Biological Process | GO:0007079 | mitotic chromosome movement towards spindle pole |
| Biological Process | GO:0007052 | mitotic spindle organization |
| Biological Process | GO:0045842 | positive regulation of mitotic metaphase/anaphase transition |
| Biological Process | GO:0007346 | regulation of mitotic cell cycle |
| Biological Process | GO:0023052 | signaling |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.