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Overview

Uniprot IDQ15697
Protein NameZinc finger protein 174
Gene NameZNF174
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
204 LLQEPTPKLAGTEAP

Function

Transcriptional repressor

Protein Sequence

10 MAAKMEITLS 20 SNTEASSKQE 30 RHIIAKLEEK 40 RGPPLQKNCP 50 DPELCRQSFR 60 RFCYQEVSGP 70 QEALSQLRQL 80 CRQWLQPELH 90 TKEQILELLV 100 MEQFLTILPP 110 EIQARVRHRC 120 PMSSKEIVTL 130 VEDFHRASKK 140 PKQWVAVCMQ 150 GQKVLLEKTG 160 SQLGEQELPD 170 FQPQTPRRDL 180 RESSPAEPSQ 190 AGAYDRLSPH 200 HWEKSPLLQE 210 PTPKLAGTEA 220 PRMRSDNKEN 230 PQQEGAKGAK 240 PCAVSAGRSK 250 GNGLQNPEPR 260 GANMSEPRLS 270 RRQVSSPNAQ 280 KPFAHYQRHC 290 RVEYISSPLK 300 SHPLRELKKS 310 KGGKRSLSNR 320 LQHLGHQPTR 330 SAKKPYKCDD 340 CGKSFTWNSE 350 LKRHKRVHTG 360 ERPYTCGECG 370 NCFGRQSTLK 380 LHQRIHTGEK 390 PYQCGQCGKS 400 FRQSSNLHQH HRLHHGD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000785 chromatin
Cellular Component GO:0001650 fibrillar center
Cellular Component GO:0016604 nuclear body
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003700 DNA-binding transcription factor activity
Molecular Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Function GO:0042803 protein homodimerization activity
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Function GO:0043565 sequence-specific DNA binding
Molecular Function GO:1990837 sequence-specific double-stranded DNA binding
Molecular Function GO:0000976 transcription cis-regulatory region binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0006357 regulation of transcription by RNA polymerase II

Reference

PMID: N/A