Search Results
Overview
| Uniprot ID | Q15814 |
|---|---|
| Protein Name | Tubulin-specific chaperone C |
| Gene Name | TBCC |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 173 | QDSPLPKKAEGDLGP |
| 96 | SRLQGLQKLINDSVF |
Function
Tubulin-folding protein; involved in the final step of the tubulin folding pathway
Protein Sequence
10
MESVSCSAAA
20
VRTGDMESQR
30
DLSLVPERLQ
40
RREQERQLEV
50
ERRKQKRQNQ
60
EVEKENSHFF
70
VATFVRERAA
80
VEELLERAES
90
VERLEEAASR
100
LQGLQKLIND
110
SVFFLAAYDL
120
RQGQEALARL
130
QAALAERRRG
140
LQPKKRFAFK
150
TRGKDAASST
160
KVDAAPGIPP
170
AVESIQDSPL
180
PKKAEGDLGP
190
SWVCGFSNLE
200
SQVLEKRASE
210
LHQRDVLLTE
220
LSNCTVRLYG
230
NPNTLRLTKA
240
HSCKLLCGPV
250
STSVFLEDCS
260
DCVLAVACQQ
270
LRIHSTKDTR
280
IFLQVTSRAI
290
VEDCSGIQFA
300
PYTWSYPEID
310
KDFESSGLDR
320
SKNNWNDVDD
330
FNWLARDMAS
340
PNWSILPEEE
RNIQWD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0007021 | tubulin complex assembly |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0032391 | photoreceptor connecting cilium |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0051087 | protein-folding chaperone binding |
| Molecular Function | GO:0015631 | tubulin binding |
| Biological Process | GO:0007023 | post-chaperonin tubulin folding pathway |
| Biological Process | GO:0006457 | protein folding |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.