Search Results

Overview

Uniprot IDQ16568
Protein NameCocaine- and amphetamine-regulated transcript protein
Gene NameCARTPT
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
74 KRVPIYEKKYGQVPM

Function

Satiety factor closely associated with the actions of leptin and neuropeptide Y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro

Protein Sequence

10 MESSRVRLLP 20 LLGAALLLML 30 PLLGTRAQED 40 AELQPRALDI 50 YSAVDDASHE 60 KELIEALQEV 70 LKKLKSKRVP 80 IYEKKYGQVP 90 MCDAGEQCAV 100 RKGARIGKLC 110 DCPRGTSCNS FLLKCL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005615 extracellular space
Cellular Component GO:0043025 neuronal cell body
Cellular Component GO:0030141 secretory granule
Cellular Component GO:0045202 synapse
Molecular Function GO:0005184 neuropeptide hormone activity
Biological Process GO:0008343 adult feeding behavior
Biological Process GO:0048148 behavioral response to cocaine
Biological Process GO:0006171 cAMP biosynthetic process
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0009267 cellular response to starvation
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0032922 circadian regulation of gene expression
Biological Process GO:1990708 conditioned place preference
Biological Process GO:0050968 detection of chemical stimulus involved in sensory perception of pain
Biological Process GO:0050965 detection of temperature stimulus involved in sensory perception of pain
Biological Process GO:0042756 drinking behavior
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0006006 glucose metabolic process
Biological Process GO:0006874 intracellular calcium ion homeostasis
Biological Process GO:0001678 intracellular glucose homeostasis
Biological Process GO:0032099 negative regulation of appetite
Biological Process GO:0045779 negative regulation of bone resorption
Biological Process GO:0051481 negative regulation of cytosolic calcium ion concentration
Biological Process GO:0046325 negative regulation of D-glucose import across plasma membrane
Biological Process GO:1903999 negative regulation of eating behavior
Biological Process GO:0070093 negative regulation of glucagon secretion
Biological Process GO:0040013 negative regulation of locomotion
Biological Process GO:0045671 negative regulation of osteoclast differentiation
Biological Process GO:1901081 negative regulation of relaxation of smooth muscle
Biological Process GO:2000675 negative regulation of type B pancreatic cell apoptotic process
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0035106 operant conditioning
Biological Process GO:0045777 positive regulation of blood pressure
Biological Process GO:0032812 positive regulation of epinephrine secretion
Biological Process GO:0045921 positive regulation of exocytosis
Biological Process GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0051971 positive regulation of transmission of nerve impulse
Biological Process GO:1904692 positive regulation of type B pancreatic cell proliferation
Biological Process GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep
Biological Process GO:0042320 regulation of circadian sleep/wake cycle, REM sleep
Biological Process GO:0010840 regulation of circadian sleep/wake cycle, wakefulness
Biological Process GO:0003062 regulation of heart rate by chemical signal
Biological Process GO:0046890 regulation of lipid biosynthetic process
Biological Process GO:0050994 regulation of lipid catabolic process
Biological Process GO:0090325 regulation of locomotion involved in locomotory behavior
Biological Process GO:0003070 regulation of systemic arterial blood pressure by neurotransmitter
Biological Process GO:0051412 response to corticosterone
Biological Process GO:0043435 response to corticotropin-releasing hormone
Biological Process GO:0045471 response to ethanol
Biological Process GO:0032094 response to food
Biological Process GO:0009749 response to glucose
Biological Process GO:0032868 response to insulin
Biological Process GO:0043278 response to morphine
Biological Process GO:0007165 signal transduction
Biological Process GO:0070253 somatostatin secretion

Reference

PMID: N/A