Search Results
Overview
| Uniprot ID | Q16663 |
|---|---|
| Protein Name | C-C motif chemokine 15 |
| Gene Name | CCL15 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 79 | ETSSECSKPGVIFLT |
Function
Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the CCL15
Protein Sequence
10
MKVSVAALSC
20
LMLVAVLGSQ
30
AQFTNDAETE
40
LMMSKLPLEN
50
PVVLNSFHFA
60
ADCCTSYISQ
70
SIPCSLMKSY
80
FETSSECSKP
90
GVIFLTKKGR
100
QVCAKPSGPG
110
VQDCMKKLKP
YSI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005615 | extracellular space |
| Molecular Function | GO:0048020 | CCR chemokine receptor binding |
| Molecular Function | GO:0042056 | chemoattractant activity |
| Molecular Function | GO:0008009 | chemokine activity |
| Molecular Function | GO:0008201 | heparin binding |
| Molecular Function | GO:0005102 | signaling receptor binding |
| Biological Process | GO:0061844 | antimicrobial humoral immune response mediated by antimicrobial peptide |
| Biological Process | GO:0060326 | cell chemotaxis |
| Biological Process | GO:0007267 | cell-cell signaling |
| Biological Process | GO:0070098 | chemokine-mediated signaling pathway |
| Biological Process | GO:0006935 | chemotaxis |
| Biological Process | GO:0006954 | inflammatory response |
| Biological Process | GO:0006874 | intracellular calcium ion homeostasis |
| Biological Process | GO:0030335 | positive regulation of cell migration |
| Biological Process | GO:0050729 | positive regulation of inflammatory response |
| Biological Process | GO:0007165 | signal transduction |
Reference
PMID: N/A