Search Results
Overview
| Uniprot ID | Q1HCL7 |
|---|---|
| Protein Name | NAD kinase 2, mitochondrial |
| Gene Name | Nadk2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 59 | SRVVVVAKTTRYEFE |
Function
Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor (By similarity)
Protein Sequence
10
MDTSAIQQTL
20
VKIYQRQAWQ
30
PPRKASKNET
40
TVGKPRELAG
50
GGSPADGGFR
60
PSRVVVVAKT
70
TRYEFEQQRY
80
RYAELSEEDL
90
KQLLALKGSS
100
YSGLLERHHI
110
HTKNVEHIID
120
SLRDEGIEVR
130
LVKRREYDEE
140
TVRWADAVIA
150
AGGDGTMLLA
160
ASKVLDRLKP
170
VIGVNTDPER
180
SEGHLCLPVR
190
YTHSFPEALQ
200
KFSRGEFRWL
210
WRQRIRLYLE
220
GTGINPSPVD
230
LHEQQLSLNQ
240
HSRAFNIERV
250
DDERSEASGP
260
QLLPVRALNE
270
VFIGESLSSR
280
ASYYEISVDD
290
GPWEKQKSSG
300
LNLCTGTGSK
310
AWSFNINRVA
320
AQAVEDVLNI
330
ARRQGNLTLP
340
LNKELVEKVT
350
NEYNESLLYS
360
PEEPKILFSI
370
REPIANRVFS
380
SSRQRCFSSK
390
VCVRSRCWDA
400
CMVVDGGTSF
410
EFNDGAIASM
420
MINKEDELRT
VILEQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0003951 | NAD+ kinase activity |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:0019674 | NAD+ metabolic process |
| Biological Process | GO:0006741 | NADP+ biosynthetic process |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.