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Overview

Uniprot IDQ29290
Protein NameCystatin-B
Gene NameCSTB
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
24 QAIADKVKSQLEEKE
30 VKSQLEEKENKTFPV
33 QLEEKENKTFPVFKA
44 VFKAVEFKSQVVAGR

Function

This is an intracellular thiol proteinase inhibitor

Protein Sequence

10 MMCGAPSATQ 20 PATAEIQAIA 30 DKVKSQLEEK 40 ENKTFPVFKA 50 VEFKSQVVAG 60 RNLFIKVQVD 70 DDDFVHLRVF 80 ESLPHENKPL 90 TLSSYQTNKS RHDELTYF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005615 extracellular space
Cellular Component GO:0005730 nucleolus
Molecular Function GO:0004869 cysteine-type endopeptidase inhibitor activity
Molecular Function GO:0002020 protease binding
Biological Process GO:1990000 amyloid fibril formation
Biological Process GO:0045861 negative regulation of proteolysis

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.