Search Results
Overview
| Uniprot ID | Q29380 |
|---|---|
| Protein Name | Non-selective voltage-gated ion channel VDAC3 |
| Gene Name | VDAC3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 12 | PTYCDLGKAAKDVFN |
| 15 | CDLGKAAKDVFNKGY |
| 163 | SFDTAKSKLSQNNFA |
| 224 | TRFGIAAKYKLDCRT |
| 34 | VKIDLRTKSCSGVEF |
| 61 | ASGNLETKYKICDHG |
Function
Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane. Forms a high-conducting channel with a stable open state and a voltage-induced closure with a mild preference for anions over cations (By similarity). Involved in male fertility and sperm mitochondrial sheath formation (By similarity)
Protein Sequence
10
MCNTPTYCDL
20
GKAAKDVFNK
30
GYGFGMVKID
40
LRTKSCSGVE
50
FSTSGHAYTD
60
TGKASGNLET
70
KYKICDHGLT
80
FTQKWNTDNT
90
LGTEISLENK
100
LAEGLKLTLD
110
TIFVPNTGKK
120
SGKLKASYKR
130
ECFSIGSNVD
140
IDFAGPTIYG
150
WAVLALEGWL
160
AGYQMSFDTA
170
KSKLSQNNFA
180
LGYKAADFQL
190
HTHVNDGTEF
200
GGSIYQKVNE
210
KIETSINLAW
220
TAGSNNTRFG
230
IAAKYKLDCR
240
TSLSAKVNNA
250
SLIGLGYTQT
260
LRPGVKLTLS
270
ALIDGKNFSA
280
GGHKVGLGFE
LEA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Cellular Component | GO:0046930 | pore complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0015288 | porin activity |
| Molecular Function | GO:0008308 | voltage-gated monoatomic anion channel activity |
| Biological Process | GO:0120317 | sperm mitochondrial sheath assembly |
| Biological Process | GO:0007283 | spermatogenesis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.