Search Results
Overview
| Uniprot ID | Q29558 |
|---|---|
| Protein Name | NADP-dependent malic enzyme |
| Gene Name | ME1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 328 | DSKGLIVKGRAALTN |
| 502 | VSLKIAEKIVRDAYQ |
Function
Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate
Protein Sequence
10
GYGLTRIPHL
20
NKDLAFTLEE
30
RQQLNIHGLL
40
PPCFISQDIQ
50
VLRVIKNFER
60
LNSDFDRYLL
70
LMDLQDRNEK
80
LFYKVLMSDI
90
EKFMPIVYTP
100
TVGLACQQYS
110
LAFRKPRGLF
120
ISIHDRGHVA
130
SVLNAWPEDV
140
IKAVVVTDGE
150
RILGLGDLGC
160
NGMGIPVGKL
170
ALYTACGGVN
180
PQECLPVILD
190
VGTENEELLK
200
DPLYIGLRQR
210
RVRGPEYDDF
220
LDEFMEAVSS
230
KYGMNCLIQF
240
EDFANINAFR
250
LLKKYQNQYC
260
TFNDDIQGTA
270
SVAVAGILAA
280
LRITKNKLSD
290
QTILFQGAGE
300
AALGIAHLIV
310
MAMEKEGVPK
320
EKAIKKIWLV
330
DSKGLIVKGR
340
AALTNEKEEF
350
AHEHEEMKNL
360
EAIVQDIKPT
370
ALIGVAAIGG
380
AFSEQILKDM
390
AAFNERPIIF
400
ALSNPTSKAE
410
CTAERGYTLT
420
QGRAIFASGS
430
PFDPVTLPSG
440
QTLYPGQGNN
450
SYVFPGVALA
460
VVACGLRHIT
470
DKIFLTTAEV
480
IAQQVSDKHL
490
EEGRLYPPLN
500
TIRDVSLKIA
510
EKIVRDAYQE
520
KTATIYPEPS
530
NKEAFVRSQM
540
YSTDYDQILP
550
DGYSWPEEAQ
KIQTKLD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0004473 | malate dehydrogenase (decarboxylating) (NADP+) activity |
| Molecular Function | GO:0004470 | malic enzyme activity |
| Molecular Function | GO:0030145 | manganese ion binding |
| Molecular Function | GO:0051287 | NAD binding |
| Molecular Function | GO:0008948 | oxaloacetate decarboxylase activity |
| Biological Process | GO:0006108 | malate metabolic process |
| Biological Process | GO:0051289 | protein homotetramerization |
| Biological Process | GO:0009725 | response to hormone |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.