Search Results
Overview
| Uniprot ID | Q29561 |
|---|---|
| Protein Name | UMP-CMP kinase |
| Gene Name | CMPK1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 16 | LGGPGAGKGTQCARI |
| 26 | QCARIVEKYGYTHLS |
| 4 | ****MRPKVVFVLGG |
Function
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity
Protein Sequence
10
MRPKVVFVLG
20
GPGAGKGTQC
30
ARIVEKYGYT
40
HLSAGELLRD
50
ERKNPDSQYG
60
ELIEKYIKDG
70
KIVPVEITIS
80
LLRREMDQTM
90
AANAQKNKFL
100
IDGFPRNQDN
110
LQGWNKTMDG
120
KADVSFVLFF
130
DCNNEICIER
140
CLERGKSSGR
150
SDDNRESLEK
160
RIQTYLQSTK
170
PIIDLYEEMG
180
KVKKIDASKS
190
VDEVFDEVVK
IFDKEG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0036430 | CMP kinase activity |
| Molecular Function | GO:0036431 | dCMP kinase activity |
| Molecular Function | GO:0004550 | nucleoside diphosphate kinase activity |
| Molecular Function | GO:0033862 | UMP kinase activity |
| Biological Process | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process |
| Biological Process | GO:0046705 | CDP biosynthetic process |
| Biological Process | GO:0006225 | UDP biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.