Search Results
Overview
| Uniprot ID | Q2KN99 |
|---|---|
| Protein Name | Cytospin-A |
| Gene Name | Specc1l |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | RSAGSVPKVSGISKP |
Function
Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration (By similarity)
Protein Sequence
10
MKKANRSAGS
20
VPKVSGISKP
30
QTVEKSKSEN
40
SSSAPTGGKP
50
VKPGAAAALS
60
KTKSNDDLLA
70
GMAGGVNVTN
80
GVKAKKSNCS
90
SAAPSAPAPA
100
MTISESKSKS
110
STGTSSSAKR
120
STSAGNKESS
130
STRERLRERT
140
RLNQSKKLPS
150
VSQGANDVAL
160
AKRSRSRTAT
170
EGDIRMSKSK
180
SDNQISDKAA
190
LEAKVKDLLT
200
LAKTKDVEIL
210
HLRNELRDMR
220
AQLGISEDHC
230
EGEDRSEEKE
240
TIIAHQPTDV
250
ESTLLQLQEQ
260
NTAIREELNQ
270
LKNENRMLKD
280
RLNALGFSLE
290
QRLDNSEKLF
300
GYQSLSPEIT
310
PGNQSDGGGT
320
LTSSVEGSAP
330
GSVEDLLSQD
340
ENTLMAHQHS
350
NSMDNLDSEC
360
SEVYQPLTSS
370
DDALDAPSSS
380
ESEGVPSIER
390
SRKGSSGNAS
400
EVSVACLTER
410
IHQMEENQHS
420
TSEELQATLQ
430
ELADLQQITQ
440
ELNSENERLG
450
EEKVILMESL
460
CQQSDKLEHF
470
GRQIEYFRSL
480
LDEHHISYVI
490
DEDVKSGRYM
500
ELEQRYMDLA
510
ENARFEREQL
520
LGVQQHLSNT
530
LKMAEQDNKE
540
AQEMIGALKE
550
RSHHMERIIE
560
SEQKGKAALA
570
ATLEEYKATV
580
ASDQIEMNRL
590
KAQLEKEKQK
600
VAELYSIHNS
610
GDKSDIQDLL
620
ESVRLDKEKA
630
ETLASSLQED
640
LAHTRNDANR
650
LQDTIAKVED
660
EYRAFQEEAK
670
KQIEDLNMTL
680
EKLRSELEEK
690
ETERSDMKET
700
IFELEDEVEQ
710
HRAVKLHDNL
720
IISDLENTVK
730
KLQDQKHDLE
740
RENKTLHRRL
750
REESAEWRQF
760
QADLQTAVVI
770
ANDIKSEAQE
780
EIGDLKRRLH
790
EAQEKNEKLT
800
KELEEIKSRK
810
QEEERGRVYN
820
YMNAVERDLA
830
ALRQGMGLSR
840
RSSTSSEPTP
850
TVKTLIKSFD
860
SASQVPNAAA
870
AAIPRTPLSP
880
SPMKTPPAAA
890
VSPMQRHSIS
900
GPVSTSKPLT
910
ALSDKRSNYG
920
EIPGQEHLLR
930
TSSTSRPASL
940
PRVPAMESAK
950
TISVSRRSSE
960
EMKRDISASE
970
GASPASLMAM
980
GTTSPQLSLS
990
SSPTASVTPS
1000
TRSRIREERK
1010
DPLSALAREY
1020
GGSKRNALLK
1030
WCQKKTEGYQ
1040
NIDITNFSSS
1050
WNDGLAFCAL
1060
LHTYLPAHIP
1070
YQELNSQEKK
1080
RNFTLAFQAA
1090
ESVGIKSTLD
1100
INEMARTERP
1110
DWQNVMLYVT
AIYKYFET
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0005911 | cell-cell junction |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0031941 | filamentous actin |
| Cellular Component | GO:0005921 | gap junction |
| Cellular Component | GO:0015630 | microtubule cytoskeleton |
| Cellular Component | GO:0005815 | microtubule organizing center |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0008013 | beta-catenin binding |
| Biological Process | GO:0030036 | actin cytoskeleton organization |
| Biological Process | GO:0034332 | adherens junction organization |
| Biological Process | GO:0061713 | anterior neural tube closure |
| Biological Process | GO:0007155 | cell adhesion |
| Biological Process | GO:0051301 | cell division |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0030835 | negative regulation of actin filament depolymerization |
| Biological Process | GO:0007026 | negative regulation of microtubule depolymerization |
| Biological Process | GO:0036032 | neural crest cell delamination |
| Biological Process | GO:0051897 | positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.