Search Results
Overview
| Uniprot ID | Q2LAP6 |
|---|---|
| Protein Name | Testin |
| Gene Name | Tes |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 101 | LTNPVAAKKNVSINT |
| 183 | EQFVKKYKSEALGVG |
| 221 | TPAAVGSKDKSAEAK |
| 80 | TTLIAKLKSDGIPMY |
| 9 | DLETKMKKMGLGHEQ |
Function
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity)
Protein Sequence
10
MDLETKMKKM
20
GLGHEQGFGA
30
PCLKCKENCE
40
GFELHFWRKI
50
CRNCKCGQEE
60
HDVLLSTEED
70
RKVGRLFEDT
80
KYTTLIAKLK
90
SDGIPMYKRN
100
VMILTNPVAA
110
KKNVSINTVT
120
YEWAPPVQNQ
130
ALARQYMQML
140
PKEKQPVAGS
150
EGAQYRKKQL
160
AKQLPAHDQD
170
PSKCHELSPK
180
EVKEMEQFVK
190
KYKSEALGVG
200
DVKLPSEMNA
210
QGDKVHNPAG
220
DRNTPAAVGS
230
KDKSAEAKKT
240
QYSCYCCKNT
250
MREGDPAIYA
260
ERAGYDKLWH
270
PACFICSTCG
280
ELLVDMIYFW
290
KNGKLYCGRH
300
YCDSEKPRCA
310
GCDELIFSNE
320
YTQAENQNWH
330
LKHFCCFDCD
340
NILAGKIYVM
350
VRDKPVCKPC
360
YVKNHAVVCQ
370
GCHNAIDPEV
380
QRVTYNNFSW
390
HASTECFLCS
400
CCSKCLIGQK
410
FMPVEGMVFC
SVECKKMMS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0008285 | negative regulation of cell population proliferation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.