Search Results
Overview
| Uniprot ID | Q2NKY5 |
|---|---|
| Protein Name | Tubulin beta chain |
| Gene Name | TUBB6 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 336 | QMLAIQNKNSSYFVE |
Function
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin
Protein Sequence
10
MREIVHIQAG
20
QCGNQIGTKF
30
WEVISDEHGI
40
DQAGGYVGDS
50
ALQLERISVY
60
YNESSSKKYV
70
PRAALVDLEP
80
GTMDSVRSGP
90
FGQLFRPDNF
100
IFGQTGAGNN
110
WAKGHYTEGA
120
ELVDSVLDVV
130
RKECEHCDCL
140
QGFQLTHSLG
150
GGTGSGMGTL
160
LISKIREEYP
170
DRIMNTFSVM
180
PSPKVSDTVV
190
EPYNATLSVH
200
QLVENTDETY
210
CIDNEALYDI
220
CFRTLKLTTP
230
TYGDLNHLVS
240
ATMSGVTTSL
250
RFPGQLNADL
260
RKLAVNMVPF
270
PRLHFFMPGF
280
APLTARGSQQ
290
YRALTVPELT
300
QQMFDAKNMM
310
AACDPRHGRY
320
LTVATVFRGP
330
MSMKEVDEQM
340
LAIQNKNSSY
350
FVEWIPNNVK
360
VAVCDIPPRG
370
LKMASTFIGN
380
STAIQELFKR
390
ISEQFSAMFR
400
RKAFLHWFTG
410
EGMDEMEFTE
420
AESNMNDLVS
430
EYQQYQDATV
440
NDGEEAFEDE
DEEEINE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0045171 | intercellular bridge |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0072686 | mitotic spindle |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0005200 | structural constituent of cytoskeleton |
| Biological Process | GO:0007017 | microtubule-based process |
Reference
PMID: N/A