Search Results
Overview
| Uniprot ID | Q2XVP4 |
|---|---|
| Protein Name | Tubulin alpha-1B chain |
| Gene Name | TUBA1B |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 163 | RLSVDYGKKSKLEFS |
| 326 | YRGDVVPKDVNAAIA |
| 336 | NAAIATIKTKRSIQF |
| 370 | VPGGDLAKVQRAVCM |
| 394 | AWARLDHKFDLMYAK |
| 401 | KFDLMYAKRAFVHWY |
| 60 | FSETGAGKHVPRAVF |
| 96 | PEQLITGKEDAANNY |
Function
Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed:7225365). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed:7225365). Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:7225365)
Protein Sequence
10
MRECISIHVG
20
QAGVQIGNAC
30
WELYCLEHGI
40
QPDGQMPSDK
50
TIGGGDDSFN
60
TFFSETGAGK
70
HVPRAVFVDL
80
EPTVIDEVRT
90
GTYRQLFHPE
100
QLITGKEDAA
110
NNYARGHYTI
120
GKEIIDLVLD
130
RIRKLADQCT
140
GLQGFLVFHS
150
FGGGTGSGFT
160
SLLMERLSVD
170
YGKKSKLEFS
180
IYPAPQVSTA
190
VVEPYNSILT
200
THTTLEHSDC
210
AFMVDNEAIY
220
DICRRNLDIE
230
RPTYTNLNRL
240
ISQIVSSITA
250
SLRFDGALNV
260
DLTEFQTNLV
270
PYPRIHFPLA
280
TYAPVISAEK
290
AYHEQLSVAE
300
ITNACFEPAN
310
QMVKCDPRHG
320
KYMACCLLYR
330
GDVVPKDVNA
340
AIATIKTKRS
350
IQFVDWCPTG
360
FKVGINYQPP
370
TVVPGGDLAK
380
VQRAVCMLSN
390
TTAIAEAWAR
400
LDHKFDLMYA
410
KRAFVHWYVG
420
EGMEEGEFSE
430
AREDMAALEK
440
DYEEVGVDSV
450
EGEGEEEGEE
Y
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0015630 | microtubule cytoskeleton |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0005200 | structural constituent of cytoskeleton |
| Biological Process | GO:0000226 | microtubule cytoskeleton organization |
| Biological Process | GO:0000278 | mitotic cell cycle |
| Biological Process | GO:0030182 | neuron differentiation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.