Search Results

Overview

Uniprot IDQ330K2
Protein NameNADH dehydrogenase (ubiquinone) complex I, assembly factor 6
Gene NameNDUFAF6
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
278 KHARSFHKTVPVKAF

Function

Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of complex I subunit MT-ND1

Protein Sequence

10 MAASAHGSVW 20 GPLRLGIPGL 30 CCRRPPLGLY 40 ARMRRLPGPE 50 VSGRSVAAAS 60 GPGAWGTDHY 70 CLELLRKRDY 80 EGYLCSLLLP 90 AESRSSVFAL 100 RAFNVELAQV 110 KDSVSEKTIG 120 LMRMQFWKKT 130 VEDIYCDNPP 140 HQPVAIELWK 150 AVKRHNLTKR 160 WLMKIVDERE 170 KNLDDKAYRN 180 IKELENYAEN 190 TQSSLLYLTL 200 EILGIKDLHA 210 DHAASHIGKA 220 QGIVTCLRAT 230 PYHGSRRKVF 240 LPMDICMLHG 250 VSQEDFLRRN 260 QDKNVRDVIY 270 DIASQAHLHL 280 KHARSFHKTV 290 PVKAFPAFLQ 300 TVSLEDFLKK 310 IQRVDFDIFH 320 PSLQQKNTLL 330 PLYLYIQSWR KTY

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Biological Process GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0005634 nucleus

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.