Search Results
Overview
| Uniprot ID | Q3B8N8 |
|---|---|
| Protein Name | Pescadillo homolog |
| Gene Name | Pes1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 440 | YIPPEKLKLLALQRG |
Function
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome
Protein Sequence
10
MGGLEKKKYE
20
RGSATNYITR
30
NKARKKLQLS
40
LPDFRRLCIL
50
KGIYPHEPKH
60
KKKVNKGSTA
70
ARTFYLIKDI
80
KFLLHEPIVN
90
KFREYKVFVR
100
KLRKAYGKSE
110
WNAVERLKDN
120
KPSYKLDHIV
130
KERYPTFIDA
140
LRDLDDALSM
150
CFLFSTFPRT
160
GKCHVQTIQL
170
CRRLTVEFMH
180
YVIAARALRK
190
VFLSIKGIYY
200
QAEVLGQPIV
210
WIAPYAFSHD
220
HPTDVDYRVM
230
ATFTEFYTTL
240
LGFVNFRLYQ
250
SLNLHYPPKI
260
ESQAQAEMKV
270
SEDTYALDSE
280
SSMEKLAALS
290
ASLARVVVPA
300
VEEAEADEFP
310
TDGEVTAQEE
320
DRRKELEAQE
330
KHKKLFEGLK
340
FFLNREVPRE
350
ALAFIIRSFG
360
GDVSWDKSLC
370
IGATYDSTDS
380
GITHQIVDRP
390
GQQTPIIGRY
400
YVQPQWVFDC
410
VNARLLLPVA
420
EYFPGVQLPP
430
HLSPFVSEKE
440
GDYIPPEKLK
450
LLALQRGEDP
460
GNLEEEEEDE
470
DDEGDDSEGD
480
GDVAVENEEE
490
VVEAESEEEE
500
EAHLSALEQQ
510
RLGGKKPQVM
520
AGTVKLEDRQ
530
RLAQEEESEA
540
KRLAIMMMKK
550
REKYLYQKIM
560
FGKRRKIREA
570
NKLAEKRKAH
580
DDAVRSEKKA
KRTRPV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0000793 | condensed chromosome |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0070545 | PeBoW complex |
| Cellular Component | GO:0030687 | preribosome, large subunit precursor |
| Molecular Function | GO:0043021 | ribonucleoprotein complex binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0008283 | cell population proliferation |
| Biological Process | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0007000 | nucleolus organization |
| Biological Process | GO:0051726 | regulation of cell cycle |
| Biological Process | GO:0042254 | ribosome biogenesis |
| Biological Process | GO:0006364 | rRNA processing |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.