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Overview

Uniprot IDQ3KQU3
Protein NameMAP7 domain-containing protein 1
Gene NameMAP7D1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
272 IINKRLSKSSATLWN
829 EAEAFLKKAVVQSPQ

Function

Microtubule-stabilizing protein involved in the control of cell motility and neurite outgrowth. Facilitate microtubule stabilization through the maintenance of acetylated stable microtubules

Protein Sequence

10 MESGPRAELG 20 AGAPPAVVAR 30 TPPEPRPSPE 40 GDPSPPPPPM 50 SALVPDTPPD 60 TPPAMKNATS 70 SKQLPLEPES 80 PSGQVGPRPA 90 PPQEESPSSE 100 AKSRGPTPPA 110 MGPRDARPPR 120 RSSQPSPTAV 130 PASDSPPTKQ 140 EVKKAGERHK 150 LAKERREERA 160 KYLAAKKAVW 170 LEKEEKAKAL 180 REKQLQERRR 190 RLEEQRLKAE 200 QRRAALEERQ 210 RQKLEKNKER 220 YEAAIQRSVK 230 KTWAEIRQQR 240 WSWAGALHHS 250 SPGHKTSGSR 260 CSVSAVNLPK 270 HVDSIINKRL 280 SKSSATLWNS 290 PSRNRSLQLS 300 AWESSIVDRL 310 MTPTLSFLAR 320 SRSAVTLPRN 330 GRDQGRGCDP 340 GRGPTWGRAG 350 ASLARGPQPD 360 RTHPSAAVPV 370 CPRSASASPL 380 TPCSVTRSVH 390 RCAPAGERGE 400 RRKPNAGGSP 410 APVRRRPEAS 420 PVQKKEKKDK 430 ERENEKEKSA 440 LARERSLKKR 450 QSLPASPRAR 460 LSASTASELS 470 PKSKARPSSP 480 STSWHRPASP 490 CPSPGPGHTL 500 PPKPPSPRGT 510 TASPKGRVRR 520 KEEAKESPSA 530 AGPEDKSQSK 540 RRASNEKESA 550 APASPAPSPA 560 PSPTPAPPQK 570 EQPPAETPTD 580 AAVLTSPPAP 590 APPVTPSKPM 600 AGTTDREEAT 610 RLLAEKRRQA 620 REQREREEQE 630 RRLQAERDKR 640 MREEQLAREA 650 EARAEREAEA 660 RRREEQEARE 670 KAQAEQEEQE 680 RLQKQKEEAE 690 ARSREEAERQ 700 RLEREKHFQQ 710 QEQERQERRK 720 RLEEIMKRTR 730 KSEVSETKQK 740 QDSKEANANG 750 SSPEPVKAVE 760 ARSPGLQKEA 770 VQKEEPIPQE 780 PQWSLPSKEL 790 PASLVNGLQP 800 LPAHQENGFS 810 TNGPSGDKSL 820 SRTPETLLPF 830 AEAEAFLKKA 840 VVQSPQVTEV L

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005813 centrosome
Cellular Component GO:0015630 microtubule cytoskeleton
Cellular Component GO:0030496 midbody
Cellular Component GO:0005819 spindle
Biological Process GO:0000226 microtubule cytoskeleton organization

Reference

[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.