Search Results
Overview
| Uniprot ID | Q3KRD1 |
|---|---|
| Protein Name | Transcription factor ETV6 |
| Gene Name | Etv6 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 289 | PRHSVDFKQSRISED |
| 404 | RALRHYYKLNIIRKE |
Function
Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation
Protein Sequence
10
MSETPAQCSI
20
KQERISSTPP
30
ESPVASYGPS
40
TPLHVPVPRA
50
LRMEEDSIHL
60
PAHLRLQPIY
70
WSRDDVAQWL
80
KWAENEFSLR
90
PIESNTFEMN
100
GKALLLLTKE
110
DFRYRSPHSG
120
DVLYELLQHI
130
LKQRKPRILF
140
SPFFHPGNSI
150
HTKPEVLLHQ
160
NHEEDNCVQR
170
TPRTPAESLH
180
HNPPTIELLH
190
RPRSPITTNH
200
RPSPDPEQQR
210
PLRSPLDNMI
220
RRLSPAERAQ
230
GPRLQQENNH
240
QESYPLSVSP
250
MENNHCPPSS
260
ESNPKPSSPW
270
QESTRVIQLM
280
PSPIMHPLIL
290
NPRHSVDFKQ
300
SRISEDGMHR
310
EGKPINLSHR
320
EDLAYMNHIM
330
VSVSPPEEHA
340
MPIGRIADCR
350
LLWDYVYQLL
360
SDSRYENFIR
370
WEDKESKIFR
380
IVDPNGLARL
390
WGNHKNRTNM
400
TYEKMSRALR
410
HYYKLNIIRK
420
EPGQRLLFRF
430
MKTPDEIMSG
440
RTDRLEHLES
450
QELDEQAYQE
DEC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0006351 | DNA-templated transcription |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.