Search Results
Overview
| Uniprot ID | Q43312 |
|---|---|
| Protein Name | Protein H2A.7 |
| Gene Name | H2A-4 |
| Organism | Triticum aestivum |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 14 | AIGSGAAKKAISRSS |
| 6 | **MAGRGKAIGSGAA |
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Protein Sequence
10
MAGRGKAIGS
20
GAAKKAISRS
30
SKAGLQFPVG
40
RIARFLKAGK
50
YAERVGAGAP
60
VYLAAVLEYL
70
AAEVLELAGN
80
AARDNKKTRI
90
VPRHIQLAVR
100
NDEELSRLLG
110
MVTIASGGVM
120
PNIHNLLLPK
130
KAGGSKAVAA
DDDS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000786 | nucleosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030527 | structural constituent of chromatin |
| Biological Process | GO:0031507 | heterochromatin formation |
Reference
[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.