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Overview

Uniprot IDQ494R4
Protein NameDynein regulatory complex protein 12
Gene NameDRC12
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
4 ****MPPKNKEKGKK

Function

Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes

Protein Sequence

10 MPPKNKEKGK 20 KSGAQKKKKN 30 WGADVVAESR 40 HRLVVLEKEL 50 LRDHLALRRD 60 EARRAKASED 70 QLRQRLQGVE 80 AELEGARSEG 90 KAIYAEMSRQ 100 CHALQEDMQT 110 RSKQLEEEVK 120 GLRGQLEACQ 130 REAAAAREEA 140 EQALGERDQA 150 LAQLRAHMAD 160 MEAKYEEILH 170 DSLDRLLAKL 180 RAIKQQWDGA 190 ALRLHARHKE 200 QQRQFGLTPP 210 GSLRPPAPSL

Gene Ontology

Classification GO ID Description
Molecular Function GO:0042802 identical protein binding

Reference

[1] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.