Search Results
Overview
| Uniprot ID | Q499T3 |
|---|---|
| Protein Name | Tyrosine-protein phosphatase non-receptor type substrate 1 |
| Gene Name | Sirpa |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 127 | YYCVKFQKGIVEPDT |
| 417 | TRLHEPEKNAREITQ |
Function
No function data available.
Protein Sequence
10
MEPAGPAPGR
20
LGPLLFCLLL
30
SASCFCAGAS
40
GKELKVTQAD
50
KSVSVAAGDS
60
ATLNCTVSSL
70
TPVGPIKWFK
80
GEGQNRSPIY
90
SFIGGEHFPR
100
ITNVSDATKR
110
NNMDFSICIS
120
NVTPEDAGTY
130
YCVKFQKGIV
140
EPDTEIKSGG
150
GTTLYVLAKP
160
SSPEVSGPDS
170
RGSPGQTVNF
180
TCKSYGFSPR
190
NITLKWLKDG
200
KELSHLETTI
210
SSKSNVSYNI
220
SSTVSVKLSP
230
EDIHSRVICE
240
VAHVTLEGRP
250
LNGTANFSNI
260
IRVSPTLKIT
270
QQPLTPASQV
280
NLTCQVQKFY
290
PKALQLNWLE
300
NGNLSRTDKP
310
EHFTDNRDGT
320
YNYTSLFLVN
330
SSAHREDVVF
340
TCQVEHDSQP
350
AITENHTVRA
360
FAHSSSGGSM
370
ETIPDNNAYY
380
NWNVFIGVGV
390
ACALLVVLLM
400
AALYLLRIKQ
410
KKAKGSTSST
420
RLHEPEKNAR
430
EITQVQSLIQ
440
DTNDINDITY
450
ADLNLPKEKK
460
PAPRVPEPNN
470
HTEYASIETG
480
KLPRPEDTLT
490
YADLDMVHLN
500
RAQPTPKPEP
510
SFSEYASVQV
QRK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
| Molecular Function | GO:0019903 | protein phosphatase binding |
| Molecular Function | GO:0017124 | SH3 domain binding |
| Biological Process | GO:0097529 | myeloid leukocyte migration |
| Biological Process | GO:0050765 | negative regulation of phagocytosis |
| Biological Process | GO:0032675 | regulation of interleukin-6 production |
| Biological Process | GO:0045428 | regulation of nitric oxide biosynthetic process |
| Biological Process | GO:0032680 | regulation of tumor necrosis factor production |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.