Search Results
Overview
| Uniprot ID | Q4FZU3 |
|---|---|
| Protein Name | Nuclear speckle splicing regulatory protein 1 |
| Gene Name | Nsrp1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 108 | KYIHNLLKAVEIRKK |
| 14 | QYGLILPKKTQPLNR |
| 15 | YGLILPKKTQPLNRV |
| 276 | EDTGASTKYLKHHKN |
| 58 | KQAMRQTKLEIQKAL |
| 96 | NPKLLMGKDRKPKYI |
Function
RNA-binding protein that mediates pre-mRNA alternative splicing regulation (By similarity). Through CCDC118 regulation, may promote pre-adipocyte differentiation (By similarity)
Protein Sequence
10
MAIPGRQYGL
20
ILPKKTQPLN
30
RVLQKPSVFG
40
NDSDDDEASV
50
SESLQREAAK
60
KQAMRQTKLE
70
IQKALAEDST
80
VYEYDSIYDE
90
MQKKKEENNP
100
KLLMGKDRKP
110
KYIHNLLKAV
120
EIRKKEQEKR
130
MEKKIQRERE
140
MEKGEFDDKE
150
AFVTSAYKKK
160
LEERAEEEER
170
EKRAAALEAR
180
LDVTKQKDLS
190
GFYRHLLNQA
200
VGEEAVPKSS
210
FREARTVIKE
220
EKLRGYPDET
230
NSENRPQQNC
240
ALQSGVEEAE
250
ENPDADSDSE
260
ESCDDGERGD
270
HKVKSRGEED
280
TGASTKYLKH
290
HKNHTHSRSS
300
SEEGGLSTKY
310
HSRSSQSRGH
320
EHKGGQHQDR
330
QSRDQESCHK
340
DRSHREEKSS
350
HRHREASHKD
360
HHWKRHEHED
370
KPKGRGQGER
380
QDREWKREKY
390
SSREQEKDRQ
400
WNDHDRYSEK
410
EKKGKEKEEH
420
RKARRERCED
430
GAKYRERKKP
440
EGSGQSSERH
450
RDRRESSPRP
460
RPEDDLLDQE
470
RSSKARNTEK
480
DKGEQGKPPR
490
SETSLATKHR
500
LTEERPEKGS
510
QPERPPEAVS
520
KFAKRSNEET
530
VMSARDRYLA
540
RQMARINAKT
YIEKEDD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Molecular Function | GO:0003729 | mRNA binding |
| Biological Process | GO:0032502 | developmental process |
| Biological Process | GO:0001701 | in utero embryonic development |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:1904179 | positive regulation of adipose tissue development |
| Biological Process | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome |
| Biological Process | GO:0043484 | regulation of RNA splicing |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.