Search Results
Overview
| Uniprot ID | Q4JDL3 |
|---|---|
| Protein Name | Tyrosine-protein phosphatase non-receptor type 20 |
| Gene Name | PTPN20 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 264 | EIEGGIIKCYHYWPI |
Function
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates
Protein Sequence
10
MSSPRDFRAE
20
PVNDYEGNDS
30
EAEDLNFRET
40
LPSSSQENTP
50
RSKVFENKVN
60
SEKVKLSLRN
70
FPHNDYEDVF
80
EEPSESGSDP
90
SMWTARGPFR
100
RDRWSSEDEE
110
AAGPSQALSP
120
LLSDTRKIVS
130
EGELDQLAQI
140
RPLIFNFHEQ
150
TAIKDCLKIL
160
EEKTAAYDIM
170
QEFMALELKN
180
LPGEFNSGNQ
190
PSNREKNRYR
200
DILPYDSTRV
210
PLGKSKDYIN
220
ASYIRIVNCG
230
EEYFYIATQG
240
PLLSTIDDFW
250
QMVLENNSNV
260
IAMITREIEG
270
GIIKCYHYWP
280
ISLKKPLELK
290
HFRVFLENYQ
300
ILQYFIIRMF
310
QVVEKSTGTS
320
HSVKQLQFTK
330
WPDHGTPASA
340
DSFIKYIRYA
350
RKSHLTGPMV
360
VHCSAGIGRT
370
GVFLCVDVVF
380
CAIVKNCSFN
390
IMDIVAQMRE
400
QRSGMVQTKE
410
QYHFCYDIVL
420
EVLRKLLTLD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0034451 | centriolar satellite |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0004721 | phosphoprotein phosphatase activity |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.