Search Results
Overview
| Uniprot ID | Q4KLN7 |
|---|---|
| Protein Name | ADP-ribosylation factor GTPase-activating protein 3 |
| Gene Name | Arfgap3 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 216 | AEVSSIIKKKPNQAK |
| 341 | TLAKPRRKYQEDPED |
| 401 | RDPEPATKSTGSSDR |
Function
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity)
Protein Sequence
10
MGDPSKQDIL
20
AIFKRLRSVP
30
TNKVCFDCGA
40
KNPSWASISY
50
GVFLCIDCSG
60
SHRSLGVHLS
70
FIRSTELDSN
80
WSWFQLRCMQ
90
VGGNANASSF
100
FHQHGCATKD
110
TNAKYNSRAA
120
QLYREKIKTL
130
ATQATRRHGT
140
DLWLDSCAAP
150
PASPPPKEED
160
FFASHASLEV
170
SGATQASAQP
180
EPASSTPWGL
190
ETTPEKHEGG
200
PGQGPSVEGL
210
NTPGKTAPAE
220
VSSIIKKKPN
230
QAKKGLGAKK
240
GSLGAQKLTN
250
TSFTEIEKQA
260
QAVDKRKEQE
270
DLARGTPKEE
280
SIVSSLRLAY
290
KDLEIHKKQD
300
ERLNLSGQKK
310
AEAERLGMGF
320
GSCRGGISHS
330
VTSDMQTIEQ
340
ESPTLAKPRR
350
KYQEDPEDSY
360
FSSSSKWSEQ
370
SSSRYFDDPM
380
ELRSSHFSSW
390
DDSADSYWKK
400
DSSRDPEPAT
410
KSTGSSDRPS
420
SRRKPEYEPV
430
GNTDEAQKKF
440
GNVKAISSDM
450
YFGIQSQTDF
460
ETRARLERLS
470
TSSSISSADL
480
FDEQRKQTTG
490
NYNLSNVLPN
500
APDMAQFKQG
510
VRSVAGKLSV
520
FANGVMTSIQ
DRYGS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0098684 | photoreceptor ribbon synapse |
| Cellular Component | GO:0048786 | presynaptic active zone |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0048205 | COPI coating of Golgi vesicle |
| Biological Process | GO:0140238 | presynaptic endocytosis |
| Biological Process | GO:0009306 | protein secretion |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.