Search Results
Overview
| Uniprot ID | Q4KM31 |
|---|---|
| Protein Name | LIM domain-containing protein 2 |
| Gene Name | Limd2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 100 | FQQLFKSKGNYDEGF |
| 98 | PHFQQLFKSKGNYDE |
Function
Acts as an activator of the protein-kinase ILK, thereby regulating cell motility
Protein Sequence
10
MFQAAGAAQA
20
TPSHEAKGSS
30
GNSTVQRSKS
40
FSLRAQVKET
50
CAACQKTVYP
60
MERLVADKLI
70
FHNSCFCCKH
80
CHTKLSLGSY
90
AAMHGEFYCK
100
PHFQQLFKSK
110
GNYDEGFGRK
120
QHKELWAHKE
VDSGTKTA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0051015 | actin filament binding |
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0051017 | actin filament bundle assembly |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.