Search Results
Overview
| Uniprot ID | Q4KM74 |
|---|---|
| Protein Name | Vesicle-trafficking protein SEC22b |
| Gene Name | Sec22b |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 124 | TFIQKTKKLYIDSRA |
| 169 | ALSALDSKANNLSSL |
Function
SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER
Protein Sequence
10
MVLLTMIARV
20
ADGLPLAASM
30
QEDEQSGRDL
40
QQYQSQAKQL
50
FRKLNEQSPT
60
RCTLEAGAMT
70
FHYIIEQGVC
80
YLVLCEAAFP
90
KKLAFAYLED
100
LHSEFDEQHG
110
KKVPTVSRPY
120
SFIEFDTFIQ
130
KTKKLYIDSR
140
ARRNLGSINT
150
ELQDVQRIMV
160
ANIEEVLQRG
170
EALSALDSKA
180
NNLSSLSKKY
190
RQDAKYLNMR
200
STYAKLAAVA
210
VFFIMLIVYV
RFWWL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030137 | COPI-coated vesicle |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment |
| Cellular Component | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane |
| Cellular Component | GO:0012507 | ER to Golgi transport vesicle membrane |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0042470 | melanosome |
| Cellular Component | GO:0031201 | SNARE complex |
| Cellular Component | GO:0008021 | synaptic vesicle |
| Molecular Function | GO:0005484 | SNAP receptor activity |
| Molecular Function | GO:0019905 | syntaxin binding |
| Biological Process | GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport |
| Biological Process | GO:1902902 | negative regulation of autophagosome assembly |
| Biological Process | GO:0045732 | positive regulation of protein catabolic process |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0006890 | retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| Biological Process | GO:0048280 | vesicle fusion with Golgi apparatus |
| Biological Process | GO:0016192 | vesicle-mediated transport |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.