Search Results
Overview
| Uniprot ID | Q505J6 |
|---|---|
| Protein Name | Mitochondrial glutamate carrier 2 |
| Gene Name | Slc25a18 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 47 | RLQNQQGKDVYKGMT |
Function
Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (symport system)
Protein Sequence
10
MIACRMSSQD
20
LSITAKLING
30
GIAGLVGVTC
40
VFPIDLAKTR
50
LQNQQGKDVY
60
KGMTDCLVKT
70
ARAEGFLGMY
80
RGAAVNLTLV
90
TPEKAIKLAA
100
NDFLRQLLMQ
110
DGTQRNLKME
120
MLAGCGAGIC
130
QVVITCPMEM
140
LKIQLQDAGR
150
LAVCQQASAS
160
ATPTSRPYST
170
GSTSTHRRPS
180
ATLIAWELLR
190
TQGLSGLYRG
200
LGATLLRDIP
210
FSIIYFPLFA
220
NLNQLGVSEL
230
TGKASFTHSF
240
VAGCAAGSVS
250
AVAVTPLDVL
260
KTRIQTLKKG
270
LGEDTYRGVT
280
DCARKLWTQE
290
GAAAFMKGAG
300
CRALVIAPLF
310
GIAQGVYFIG
320
IGERILKCFE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Molecular Function | GO:0005280 | amino acid:proton symporter activity |
| Molecular Function | GO:0015183 | L-aspartate transmembrane transporter activity |
| Molecular Function | GO:0005313 | L-glutamate transmembrane transporter activity |
| Biological Process | GO:0015810 | aspartate transmembrane transport |
| Biological Process | GO:0015813 | L-glutamate transmembrane transport |
| Biological Process | GO:0043490 | malate-aspartate shuttle |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.