Search Results
Overview
| Uniprot ID | Q562C2 |
|---|---|
| Protein Name | Ribosome biogenesis protein BOP1 |
| Gene Name | Bop1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 173 | FWRTVQDKMTGSDLR |
| 18 | SPGSLPGKRRLEPDQ |
Function
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome
Protein Sequence
10
MAGACGKHHM
20
SPGSLPGKRR
30
LEPDQEPQIQ
40
EPLLLSDPDS
50
SLSDSEESVF
60
SGLEDSGSDT
70
SDEDTEEVAR
80
AGCDKDNRTE
90
KTSEEQEQAV
100
PPCPRAEEAG
110
ALTRDEYEED
120
SSDEEDIRNT
130
VGNVPLAWYD
140
DFPHVGYDLD
150
GKRIYKPLRT
160
RDELDQFLDK
170
MDDPDFWRTV
180
QDKMTGSDLR
190
LTDEQVALVH
200
RLQRGQFGDS
210
GFDPYEPAVD
220
FFSGDIMIHP
230
VTNRPADKRS
240
FIPSLVEKEK
250
VSRLVHAIKM
260
GWIKPRRPPD
270
STPSFYDLWA
280
QEDPNAVLGR
290
HKMHVPAPKL
300
ALPGHAESYN
310
PPPEYLPTEE
320
ERLAWMQQEP
330
IERKLNFLPQ
340
KFPSLRTVPA
350
YGRFIQERFE
360
RCLDLYLCPR
370
QRKMRVNVDP
380
EDLIPKLPRP
390
RDLQPFPVCQ
400
ALVYRGHSDL
410
VRCLSVSPGG
420
QWLASGSDDG
430
TLRLWEVATA
440
RCMKTVRVGG
450
VIRSIAWNPN
460
PTICLVAAAM
470
DDAVVLLNPA
480
LGDRLLVGST
490
DQLLETFTPP
500
EEPTLQPAHW
510
LEVSEEERQR
520
GLRLRICHSK
530
PVTQVTWHGR
540
GDYLAVVLSS
550
QGHTQVLIHQ
560
LSRRRSQSPF
570
RRSHGQVQCV
580
AFHPTRPFLL
590
VASQRSIRIY
600
HLLRQELTKK
610
LMPNCKWVSS
620
MAVHPAGDNI
630
ICGSYDSKLV
640
WFDLDLSTKP
650
YKVLRHHKKA
660
LRAVAFHPRY
670
PLFASGSDDG
680
SVIVCHGMVY
690
NDLLQNPLLV
700
PVKVLKGHSL
710
TRDLGVLDVA
720
FHPTQPWVFS
730
SGADGTIRLF
S
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0070545 | PeBoW complex |
| Cellular Component | GO:0030687 | preribosome, large subunit precursor |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Molecular Function | GO:0043021 | ribonucleoprotein complex binding |
| Biological Process | GO:0008283 | cell population proliferation |
| Biological Process | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0000460 | maturation of 5.8S rRNA |
| Biological Process | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0051726 | regulation of cell cycle |
| Biological Process | GO:1901796 | regulation of signal transduction by p53 class mediator |
| Biological Process | GO:0000027 | ribosomal large subunit assembly |
| Biological Process | GO:0042273 | ribosomal large subunit biogenesis |
| Biological Process | GO:0006364 | rRNA processing |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.