Search Results
Overview
| Uniprot ID | Q562R1 |
|---|---|
| Protein Name | Beta-actin-like protein 2 |
| Gene Name | ACTBL2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 119 | NPKINREKMTQIMFE |
| 292 | KCDVDIRKDLYANTV |
| 329 | APSTMKIKIIAPPER |
| 85 | TNWDDMEKIWYHTFY |
Function
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells
Protein Sequence
10
MTDNELSALV
20
VDNGSGMCKA
30
GFGGDDAPRA
40
VFPSMIGRPR
50
HQGVMVGMGQ
60
KDCYVGDEAQ
70
SKRGVLTLKY
80
PIEHGVVTNW
90
DDMEKIWYHT
100
FYNELRVAPD
110
EHPILLTEAP
120
LNPKINREKM
130
TQIMFEAFNT
140
PAMYVAIQAV
150
LSLYASGRTT
160
GIVMDSGDGV
170
THIVPIYEGY
180
ALPHAILRLD
190
LAGRDLTDYL
200
MKILTERGYN
210
FTTTAEREIV
220
RDVKEKLCYV
230
ALDFEQEMVR
240
AAASSSPERS
250
YELPDGQVIT
260
IGNERFRCPE
270
AIFQPSFLGI
280
ESSGIHETTF
290
NSIMKCDVDI
300
RKDLYANTVL
310
SGGSTMYPGI
320
ADRMQKEIIT
330
LAPSTMKIKI
340
IAPPERKYSV
350
WIGGSILASL
360
STFQQMWISK
370
QEYDEAGPPI
VHRKCF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015629 | actin cytoskeleton |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0035267 | NuA4 histone acetyltransferase complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0098973 | structural constituent of postsynaptic actin cytoskeleton |
| Biological Process | GO:0007409 | axonogenesis |
| Biological Process | GO:0048870 | cell motility |
| Cellular Component | GO:0005884 | actin filament |
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005737 | cytoplasm |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.
[3] Guo X, Ren X, Yan C, Huang H. Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells.. ACS Chem Biol 20(7):1728-1738. 2025 Jul 18. PMID: 40590393.