Search Results
Overview
| Uniprot ID | Q56P28 |
|---|---|
| Protein Name | PRA1 family protein 3 |
| Gene Name | ARL6IP5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 151 | LKNKLENKIEGIGLK |
| 158 | KIEGIGLKRTPMGIV |
| 31 | PDFRDISKWNNRVVS |
Function
Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner. Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum
Protein Sequence
10
MDVNIAPLRA
20
WDDFFPGSDR
30
FARPDFRDIS
40
KWNNRVVSNL
50
LYYQTNYLVV
60
AAMMISVVGF
70
LSPFNMILGG
80
IVVVLVFTGF
90
VWAAHNKDIL
100
RRLKKQYPTV
110
FVMVVMLASY
120
FLISMFGGVM
130
VFVFGITFPL
140
LLMFIHASLR
150
LRNLKNKLEN
160
KIEGIGLKRT
170
PMGIVLDALE
180
QQEENISKFA
DYISKVNE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Biological Process | GO:0015813 | L-glutamate transmembrane transport |
| Biological Process | GO:0002037 | negative regulation of L-glutamate import across plasma membrane |
| Biological Process | GO:0051051 | negative regulation of transport |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.