Search Results
Overview
| Uniprot ID | Q56VL3 |
|---|---|
| Protein Name | OCIA domain-containing protein 2 |
| Gene Name | OCIAD2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 53 | CQEESFWKRALPFSL |
Function
Has an essential role in the assembly of mitochondrial respiratory chain complex III (PubMed:35080992). Is also required for STAT3 activation and plays a role in cell migration (PubMed:29743632)
Protein Sequence
10
MASASARGNQ
20
DKDAHFPPPS
30
KQSLLFCPKS
40
KLHIHRAEIS
50
KIMRECQEES
60
FWKRALPFSL
70
VSMLVTQGLV
80
YQGYLAANSR
90
FGSLPKVALA
100
GLLGFGLGKV
110
SYIGVCQSKF
120
HFFEDQLRGA
130
GFGPQHNRHC
140
LLTCEECKIK
150
HGLSEKGDSQ
PSAS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005768 | endosome |
| Biological Process | GO:0034551 | mitochondrial respiratory chain complex III assembly |
| Biological Process | GO:0046427 | positive regulation of receptor signaling pathway via JAK-STAT |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0005764 | lysosome |
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0006897 | endocytosis |
| Biological Process | GO:0061484 | hematopoietic stem cell homeostasis |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.