Search Results
Overview
| Uniprot ID | Q58FF3 |
|---|---|
| Protein Name | Putative endoplasmin-like protein |
| Gene Name | HSP90B2P |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 136 | IKKIADEKYNDTFWK |
| 143 | KYNDTFWKEFGTNIK |
| 150 | KEFGTNIKLGVIEDH |
| 322 | NYHASRKKTFEINPR |
Function
Putative molecular chaperone
Protein Sequence
10
MAETIQEVED
20
EYKAFCKSFS
30
KESDDPVACI
40
HFTAEGEVTF
50
KSILFVPTFV
60
PRGLFDEYGS
70
KKSDYIKLYV
80
RCVFITDDFR
90
DTMPKNLNFV
100
KGVVDSGGLS
110
LNVSCETLQQ
120
HKLLKVIRKK
130
LVHKTLDMIK
140
KIADEKYNDT
150
FWKEFGTNIK
160
LGVIEDHSNR
170
TCLAKLLRFQ
180
SSHHPADITS
190
LHQDVERMKE
200
KQDKICLMAG
210
GYEVIYLTEP
220
VVEYCIQALP
230
EFDGKRFQNV
240
AKEGVKFDDS
250
EKTKESHEAV
260
EKEFEPLPNW
270
VKDKAIKDKI
280
EKAMVSQCLT
290
ESLCALVASQ
300
YGWSGNMERI
310
MKAQAYQTGK
320
GISTNYHASR
330
KKTFEINPRH
340
PLIRDMLRRI
350
KEDEDDKTVL
360
DLAVVEEPDE
370
EPEETAEDKE
380
QDKDKEMDVG
390
TDEEKQETAK
ESTAEKDEL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0140662 | ATP-dependent protein folding chaperone |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:0006457 | protein folding |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Guo X, Ren X, Yan C, Huang H. Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells.. ACS Chem Biol 20(7):1728-1738. 2025 Jul 18. PMID: 40590393.
[3] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.