Search Results
Overview
| Uniprot ID | Q58FF6 |
|---|---|
| Protein Name | Putative heat shock protein HSP 90-beta 4 |
| Gene Name | HSP90AB4P |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 161 | TKVILHLKEDQTEYL |
| 446 | KSLLSVTKEGLELPE |
Function
Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins
Protein Sequence
10
MSLIINTFYS
20
NKEIFLQELI
30
SNASDALDKI
40
RYESLTDPSK
50
LDGGKELKID
60
IIPNPRECIL
70
TLVNTGIGMT
80
KADLINNLGA
90
IAKSGTEAFM
100
EAFQSCAEIS
110
MIGQFGVGFY
120
SAYLVAEKVA
130
ITKHNDEEQY
140
SWVSSAGSSF
150
TLHVDHGEPI
160
DRDTKVILHL
170
KEDQTEYLEE
180
RWVKEVVKKH
190
PQFIGCLIAV
200
YLEKEPEKEI
210
SDDEEEKGEK
220
EEEDKDDKEK
230
PKTEDVGSDE
240
EDDTDKNNKK
250
KTKKIKEKYT
260
DREELNQTKP
270
IWTRNPDDIT
280
QEECGEFYKS
290
LTSAWEDHLA
300
VKQFPVEEQE
310
ENEQLCVHHV
320
WIMDSFDDLM
330
PEYVGFVRED
340
KENNKKLDEV
350
FSKISWLGIH
360
EDSINWRHLS
370
ELLWSHTFQS
380
GDEMTSLSEY
390
VSCMKEAQKS
400
ICDIIGECKE
410
QVANSAFVEQ
420
EWKKGFEVIY
430
MSEPIDEYCV
440
QQLKEFDGKS
450
LLSVTKEGLE
460
LPEDEEEKKI
470
MEESNVKFEN
480
LCRLMKEILD
490
KKVERVTISS
500
RLVSSPCRIV
TSTYS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0140662 | ATP-dependent protein folding chaperone |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:0034605 | cellular response to heat |
| Biological Process | GO:0006457 | protein folding |
| Biological Process | GO:0050821 | protein stabilization |
| Biological Process | GO:0022618 | protein-RNA complex assembly |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.