Search Results
Overview
| Uniprot ID | Q5BJP4 |
|---|---|
| Protein Name | RNA-binding protein 39 |
| Gene Name | Rbm39 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 103 | RSPYSGPKFNSAIRG |
| 111 | FNSAIRGKIGLPHSI |
| 119 | IGLPHSIKLSRRRSR |
| 244 | AMANNLQKGSAGPMR |
Function
RNA-binding protein that acts as a pre-mRNA splicing factor. Acts by promoting exon inclusion via regulation of exon cassette splicing. Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity
Protein Sequence
10
MADDIDIEAM
20
LEAPYKKDEN
30
KLNSANGHEE
40
RSKKRKKSKS
50
RSRSHERKRS
60
KSKERKRSRD
70
RERKKSKSRE
80
RKRSRSKERR
90
RSRSRSRDRR
100
FRGRYRSPYS
110
GPKFNSAIRG
120
KIGLPHSIKL
130
SRRRSRSKSP
140
FRKDKSPVRE
150
PIDNLTPEER
160
DARTVFCMQL
170
AARIRPRDLE
180
EFFSTVGKVR
190
DVRMISDRNS
200
RRSKGIAYVE
210
FVDVSSVPLA
220
IGLTGQRVLG
230
VPIIVQASQA
240
EKNRAAAMAN
250
NLQKGSAGPM
260
RLYVGSLHFN
270
ITEDMLRGIF
280
EPFGRIESIQ
290
LMMDSETGRS
300
KGYGFITFSD
310
SECAKKALEQ
320
LNGFELAGRP
330
MKVGHVTERT
340
DASSASSFLD
350
SDELERTGID
360
LGTTGRLQLM
370
ARLAEGTGLQ
380
IPPAAQQALQ
390
MSGSLAFGAV
400
ADLQTRLSQQ
410
TEASALAAAA
420
SVQPLATQCF
430
QLSNMFNPQT
440
EEEVGWDTEI
450
KDDVIEECNK
460
HGGVIHIYVD
470
KNSAQGNVYV
480
KCPSIAAAIA
490
AVNALHGRWF
500
AGKMITAAYV
510
PLPTYHNLFP
520
DSMTATQLLV
PSRR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0010468 | regulation of gene expression |
| Biological Process | GO:0051252 | regulation of RNA metabolic process |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.