Search Results
Overview
| Uniprot ID | Q5BKX5 |
|---|---|
| Protein Name | Actin maturation protease |
| Gene Name | ACTMAP |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 82 | LEKSQLLKEAFDKAG |
Function
Actin maturation protease that specifically mediates the cleavage of immature acetylated N-terminal actin, thereby contributing to actin maturation (PubMed:36173861). Cleaves N-terminal acetylated methionine of immature cytoplasmic beta- and gamma-actins ACTB and ACTG1 after translation (PubMed:36173861). Cleaves N-terminal acetylated cysteine of muscle alpha-actins ACTA1, ACTC1 and ACTA2 after canonical removal of N-terminal methionine (By similarity)
Protein Sequence
10
MTSPCSPPLK
20
PPISPPKTPV
30
PQASSIPSPP
40
LPPSPLDFSA
50
LPSPPWSQQT
60
PVPPPLPLPP
70
PPAATGPAPR
80
HVFGLEKSQL
90
LKEAFDKAGP
100
VPKGREDVKR
110
LLKLHKDRFR
120
GDLRWILFCA
130
DLPSLIQEGP
140
QCGLVALWMA
150
GTLLSPPSGV
160
PLERLIRVAT
170
ERGYTAQGEM
180
FSVADMGRLA
190
QEVLGCQAKL
200
LSGGLGGPNR
210
DLVLQHLVTG
220
HPLLIPYDED
230
FNHEPCQRKG
240
HKAHWAVSAG
250
VLLGVRAVPS
260
LGYTEDPELP
270
GLFHPVLGTP
280
CQPPSLPEEG
290
SPGAVYLLSK
300
QGKSWHYQLW
310
DYDQVRESNL
320
QLTDFSPSRA
330
TDGRVYVVPV
340
GGVRAGLCGQ
350
ALLLTPQDCS
H
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0070005 | cysteine-type aminopeptidase activity |
| Molecular Function | GO:0004239 | initiator methionyl aminopeptidase activity |
| Biological Process | GO:0016485 | protein processing |
Reference
PMID: N/A