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Overview

Uniprot IDQ5BLZ2
Protein NamePerilipin-3
Gene NamePLIN3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
58 KESHPHVKTVCDVAE
66 TVCDVAEKGVKTLTA
69 DVAEKGVKTLTAAAV

Function

Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network

Protein Sequence

10 MFASETEASA 20 SSTQVTTEEP 30 VQQPSVVDRV 40 AGMPLISSTC 50 HMVSAAYTST 60 KESHPHVKTV 70 CDVAEKGVKT 80 LTAAAVSGAQ 90 PILSKLEPQL 100 TSASEYAHRG 110 LDKLEENLPI 120 LQQPSEKVLA 130 DTKELVSSKV 140 SEAREAVSNT 150 VSSAKDTVAS 160 RVTEAVVVTR 170 GAVQSGVDLT 180 KSMVTSSVHS 190 VMGSRVGQMV 200 LSGVDTVLGK 210 SEEWVDNHLP 220 MTDAELAHLA 230 TSLEGFDMAS 240 VAQQRQDQSY 250 FVRLGSLSER 260 LRQRAYEHSL 270 GKLQHTRQRA 280 QEALLQLSQA 290 LSLMETVKQG 300 VDQKLVEGQE 310 KLHQMWLSWN 320 QKRLQGGEED 330 PAKPEQVESQ 340 TFTMFRDVTQ 350 QLQTTCASLG 360 ASLQGLPAHV 370 KEQALQARRQ 380 VEDLQATFSG 390 MHSFQDLSSN 400 VLMQSREQVA 410 RAREALDHVV 420 DYVAQNTPVM 430 WLVGPFAPGV VEKAPEEKK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0010008 endosome membrane
Cellular Component GO:0005811 lipid droplet
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:1905691 lipid droplet disassembly
Biological Process GO:0019915 lipid storage
Biological Process GO:0010890 positive regulation of triglyceride storage

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.